I'd suggest that most Gratful Dead heads would argue differnetly. Because the dose is so small you have a greater chance of contamination during the synth. Back in the day there was a big difference in chemists and their products
Not really. "A greater chance of contamination ..." but also no contaminants involved with synthesis are remotely active at that level.
And no, there was not, is not, and really cannot be a big difference between different products assuming that they are all making real LSD and the number of mics reaching the end user are equally dosed in terms of actual LSD and not having any other drug active at such miniscule doses present (remember, we're talking contaminants at least an order of magnitude less 100mcg at worst.) What is going to be active at <10mcg? Certainly not ET, diethylamide, tartric acid, varioius solvents, etc. iso-LSD was demonstrated to be totally inactive in man even in huge doses (well in excess of 10mg) in a small, unpublished study out of one of the major universities doing research on this subject. Dose, set and setting accounts for almost all the variance in experience. Don't eat the brown acid, etc.
This is a copy paste summery...
ChinaCat72 from the Shroomery v. >2015 >people still believe this said:
a big load of hippy bullshit
FTFY. I'm a deadhead and hippies who spin these tales have no idea what they're talking about. This has been discussed
ad nauseum here so I won't get into refuting it. TL;DR the dude (now deceased) was a liar, exaggerator, and burnt out lot trash. He probably did move serious acid but things are not done the way he says they are and never were, and the alleged "crystal lines" are talked about by him and to this day on lot, simply don't exist, it's all marketing. Does LSD of varying purity exist? Sure. Does the variance effect the appearance? Not like ChinaCat describes. Does it effect the experience? Hardly. Does LSD of 90+% purity regularly reach the end user? No way.
As regards 1P-LSD, I'm really very interested to hear that there is such variance in people's responses to it, as I understand it it's recently been shown to be an LSD pro-drug which is responsible for most (all?) of the activity, so perhaps we could be looking at enzymatic variations in people taking it, or differences in product (for similar reasons to LSD, i.e. ultralow doses, contamination with actives is unlikely.) Blotters bought from some guy with an email address and a PGP key, however, could have anything on it unless you test it, for that matter ... very interesting stuff. I'll be watching this as it develops further ...