Opioids The Ultimate Opiate Potentiation Thread

[sp0r]

cyclobenzaprine

I find cyclobenzaprine to be entirely to antichollinergic. Am I right? When it comes to muscle relaxers I pick soma first and am still curious about baclofen.
sp0r

does anyone know anything about potentiating tapentadol? (nucynta)
theres not enough info out on it yet to see how it is metabolized and what the metabolites are etc.
I have it scripted for a pinched nerve in my back. I get 90 100mg pills a month, along with 30 30mg cyclobenzaprine ER (for severe insomnia)

I find tapentadol to be really enjoyable, it has a great body high (especially when combined with the cyclobenzaprine)

 

[sp0r]

Promethazine

What are people's experience with promethazine?

Promethazine is an antipsychotic/antiemetic.. Not very safe of a medicine, however some people like it. I tend to stay away from it unless trying to potentiate methadone.
sp0r

 

[sp0r]

Potentiating opiates with controversial method

Ok this is by far a controversial method but let me explain it. First go on erowid, select plants and chemicals, then select DXM.. Read the DXM FAQby William White. You need to read this because all of the dangers of DXM.. Once you learn how to trip off of DXM, you have found the greatest opiate potentiater there is. I would recommend doing a second plateau trip, comming down, then doing your opiate. Your dependance will be almost completely reverse and say you do a bag of heroin you will be bouncing off the walls.. be careful tho because you will get SUPER high. When I was on methadone I used to eat a 1/3 of a bottle of ROBO MAX cough gels 45 minutes before dosing my meth.. I GOT SOOOO fucking high for the whole day that I would be falling over, blacking out, and being extremely euphoric. There is no better potentiator than Dextromethorphan HBR. Please believe me because I have done extensive research scientifically and on myself and it always works. Ok now that is the best.
Second best IMO is Antichollinergics like diphenhydramine, diphenhydrimate, or flexaril.
Third IMO would be benzo diazepines. Best being Alprazolam for some odd reason if you are a non smoker, Second being diazepam because it has an awful long half life, and maybe third being Lorazepam because of its high.
Im not sure if this is Fourth but it did alot of good for me, and that is Soma. Becareful of your dose tho because you have a high chance of blacking out or getting arrested.
In summary be careful with 1, 3, and 4. 2 is probably the safest, and one probably the most dangerous, especially with methadone but also the best.

Do research, be careful, and enjoy.

sp0r

 

[sp0r]

Ok while this recipe may get you high, it is also dangerous. I think your main high is because of the high doseage of opiates you're on and the grapefruit juice. You dont need the gfj however, just buy some cimetidine for the cyp3a4 inhibition. It works alot better. Also I mentioned this before but will mention again, promethazine is not a good choice; it is dysphoric, and not safe. Benadryl aka diphenhydramine is a great choice. Darvocet is very toxic when mixed with other drugs. I just recently got a huge prescription of 600mg Neurontin pills and am not exactly sure about this one. Can you explain how it potentiates a little more? I am very curious, and curious about this med in general. I also received a huge prescription of baclofen. Most of all I warn you about the Darvocet. I suggest you go to drugs.com and go to the drugs interaction link and put Darvocet on the list, along with all of your other list. For some reason it doesnt mix with other drugs and is highly toxic. This link may have been posted somewhere in this thread but I dont feel like scrolling through all 40 pages. It is a wealth of information: http://psy.psychiatryonline.org/cgi/reprint/44/6/515.pdf <--
My recomendation is diphenhydramine, hydroxyzine, benzos, and cimetidine. Bon apetite.
sp0r

I got a nice little cocktail going on. 30mg of Roxi + 40mg OC + 25mg of promethazine + 20 mg of cyclobenzaprine + 100mg Darvocet + 300mg of Neurontin + 25mg of Benadryl and to top it all off some white grapefruit juice which was definitely the topping on the cake. I'm nodding off pretty damn hard right now, I havent been this fucked up n a loooong time. The best part is i'm prescribed to all of this for my chronic neck pain. I don't usually take the promethazine on a regular basis unless im sick and today was my first day to try the grapefruit juice and let me tell you it's made all the difference. Like I said this is my daily regiment i just added the GFJ, promethazine, darvocet, and an extra cyclobenzaprine. I've never felt fucked up like this on my regular dose because my tolerance is so out the roof. Otherwise it would have taken me 2 more roxi's and 2 more oxys to feel close to this. Good info here in this thread! I read it start to finish and am pleased with the results yielded! Now hopefully I don't run out of my oxys and roxis before I go back to my surgeon cause I wont have to take as many.

 

[BlueberryfishY]

Ok guys so i've been reading around in this thread, and so far i have tried advil PM with my Roxi 15's, and boy o boy did that kick it up a fucking notch! i usually take 4, 15's and feel really nice but no where close to nodding, well i did the same thing but took 2 advil PM's and i was fading in and out like a dying lightbug.

i was thinking how good is the grapefruit juice deal? and do i have to eat the pills or can i snort them and then drink the juice? any ideas?

 

[gaia34]

I skimmed the thread, and didn't seem to see anything about Baclofen, so I figured I'd add my two-cents.
I've taken it only with Oxycodone, but it does seem to be a pretty good boost to the high.
Try a lower dose though, say 10 or 20mgs so you don't fall asleep and avoid those lovely opiate feelings.
Enjoy xx

 

[NiteShadeX]

I have a low opiate tolerance to begin with, but with this setup I can take even less of my opiate of choice.

75mg Diphenhydramine Oral
20 MINUTES LATER
30mg Roxicodone Snorted
TONS OF CAFFEINE......DR.PEPPER :D

 

[Arobskittle]

why caffeine and dr pepper?

 

[psychalysis]

Opiate Potentiation Attempt

Trust this is still relevant:

One Oxycodone 10mg was taken on empty stomach with a small full strength beer (within a half hour.)
Half to an hour later, approximately 30mg or so of codeine was CWE'd and ingested.
Over the course of the next two hours, somewhere between 1 or two more small full strength beers were consumed and a couple of puffs on a joint.
(That's as detailed I can be about times and dosage.)
Other relevent info:
[/LIST]First time OC use.
[/LIST]A day or two break from a regular 100- 150mg codeine CWE 'habit' was taken beforehand. (2-3 times a week, on and off over the last 2-3 years)

This amounted to an uncomfortably 'heavy' stoning with little euphoria, a feeling of being too conscious of having to focus on breathing, concern about puffing anymore of a joint and or cigarettes and a prolonged and crappy 'after-glow.'

 

[homeydontplaythat]

Lyrics is waaaaay better than neurontin. U haven't even tried it. Just as good as Xanax for potentiation anxiety and opiate we. Suboxone can actually b euphoric and give a rush/nod w it

 

[regfairfield]

would tums work... i always assume it would kill the buzz

 

[jamesBrown]

why would tums kill the buzz?

 

[Darkhawk007]

Ok this is by far a controversial method but let me explain it. First go on erowid, select plants and chemicals, then select DXM.. Read the DXM FAQby William White. You need to read this because all of the dangers of DXM.. Once you learn how to trip off of DXM, you have found the greatest opiate potentiater there is. I would recommend doing a second plateau trip, comming down, then doing your opiate. Your dependance will be almost completely reverse and say you do a bag of heroin you will be bouncing off the walls.. be careful tho because you will get SUPER high. When I was on methadone I used to eat a 1/3 of a bottle of ROBO MAX cough gels 45 minutes before dosing my meth.. I GOT SOOOO fucking high for the whole day that I would be falling over, blacking out, and being extremely euphoric. There is no better potentiator than Dextromethorphan HBR. Please believe me because I have done extensive research scientifically and on myself and it always works.

sp0r

Jesus, thats pretty nuts man. I like taking 1-2 of the cough gels before doing my opiates, but thats just the recommended dose. I couldn't imagine going through a 2nd plateau trip just for potentiating, sounds like more trouble than its worth.

I mean I used to like tripping on large amounts of dmx many years ago but I can't stand anything over the recomended dosage now. Just makes me feel weird and really disconnected from everything. I could see how that would have you feeling pretty messed up though with that combo, I just don't think I could really enjoy my opiates at that level, thats just me though, I know a lot of people do enjoy it.

 

[Electronica7]

Ok, so I have been reading this post, and have decided to start experimenting with potentiators to opiates.

A little background information on me and my situation first, I have been on hydrocodone for about 8 years, daily for about 4 years, and as we all know, with that much experience my tolerance is through the roof. I also take oxys every now and again when I can get my hands on them, and I also drink PPT at least 3 times a week, so I am definitely not opiate naive.

So after reading through this thread, I decided to do some experimentation with potentiating my hydrocodone. I have only taken norco today, no PPT or anything else, and before my evening dose (which tonight was 6 10/325 norco at once), I took two Cimetedine, about 45 minutes before my dose, as instructed. I have to say, I haven't felt this much from norco in a very long time, and it's great!! Anyone who is thinking about trying Cimetedine before taking hydrocodone, I highly recommend it, it has worked wonders for me, and I will be doing this from now on, as well as trying other potentiators listed on this thread. I will keep you guys up to date on my experiments!

 

[lozgod]

Is it me or does the acetimetophen in percocet potentiate it? If I pop 10 10/325s I am higher than popping 4 30s.

 

[sp0r]

Well you are right in some sense, its hard not to nod out after doing dxm. But it really does lower your tolerance hard core and is an amazing potentiator.. It all depends on what you are willing to go through to get slaughtered off of opiods. But if your not willing to do all that work then for most opiods I would say cimetidine, diphenhydramine, a little dxm, and a benzo. Also quinine works good on h eorin

 

[Eagleman]

Today I acquired a large quantity of Tylenol 3. I popped 10, so 300 mg of codeine. Normally this would just make me warm and fuzzy and extremely itchy. But today I used quinine (drank a liter of tonic water about half an hour before dosing, then sipped at 20 oz. throughout the high). This is the best codeine high I've ever experienced. It had a very intense onset, more like hydro- or oxycodone. The duration was also affected--normally codeine keeps me floaty for only a couple hours, but I dosed five hours ago and I'm still feeling very euphoric.
I know it's not placebo because I never really enjoyed codeine in the past. Quinine works!
Still very itchy though...shoulda took an antihistamine I suppose

 

[upstate]

New experience

I red an old study(1980) that discussed tryptophan loading for decreasing tolerance. I was using 15-20 10/325 Norco's a day for quite a while. I ran out about 2 weeks ago, and started taking 4g a day. I had absolutely NO withdrawl symptoms(and I would normally be climbing the walls!). I should be picking up a refill tomorrow, so we'll see what it did for tolerance.

The bottom line is: I've been trying to quit for years. The major thing stopping me was the withdrawls. After the past 2 weeks, I feel better then I have in years. I think that is partly because the L-T is a direct precursor to seritonin. After the past 3 years of being on eery opiate you can think of(Ankle fusion and nerve damage), I'm sure I've killed most of my normal seritonin. Just have to be careful not to take too much morebecause of seritonin syndrome(apparently a real bitch). There is a seritonin supp. you can get at GNC or a health food store, but it's hard to find. If you can't get that, there is a sleep aid called Alteril, that has 350 MG, and if you take about 15 over 4-5 hours at night, it help with the insomnia, and you should be good the whole next day.

Just my $.02. Hope it works for somebody else!%)

 

[opiatekrzy]

i never seen anyone get over 120mgs of methadone at a clinic. i have an appt. monday to get dosed, but i got to drive downtown everyday to get it, which im so undecided, as im on suboxone and klonopin from my sub doc, i dont wanna lose my benzo script and 90 subs which i can do what choose with them,they kill my W/D. i guess i want methadone for a buzz..im sticking with my sub doc, he gives me klonpin 3x a day, 2 1/2 subs a day,, he is so nice calls in 5 day supply on a sunday if i call his personal cell, gives me medicine for headaches if i need it, Fiorional (barbiturate) known him 2 yrs, i rather not lose my relationship with him over a dumb clinic methadone wth over 700 people, and ill never get a benzo sxcript ill be labeled all over on methadone to doctors

 

[sp0r]

sorry for the long quote

I dont want to sound like a know it all, but you really have to potentiate codeine different than most opiate/opiods. It works on different metabolization than most such as oxycodone and hydrocodone. IN fact, it can be dangerous to use the normal potentiating methods with codeine. Plus google potentiating codeine or something around those lines.
sincerely,
sp0r

Today I acquired a large quantity of Tylenol 3. I popped 10, so 300 mg of codeine. Normally this would just make me warm and fuzzy and extremely itchy. But today I used quinine (drank a liter of tonic water about half an hour before dosing, then sipped at 20 oz. throughout the high). This is the best codeine high I've ever experienced. It had a very intense onset, more like hydro- or oxycodone. The duration was also affected--normally codeine keeps me floaty for only a couple hours, but I dosed five hours ago and I'm still feeling very euphoric.
I know it's not placebo because I never really enjoyed codeine in the past. Quinine works!
Still very itchy though...shoulda took an antihistamine I suppose