Still wonder about
pemoline, it's off-market almost everywhere but apparently still used in Japan, and is said to behave different than either amphetamine or methylphenidate, with less tolerance issues, minimal sympathomimetic side effects and the magnesium salt having some nootropic properties (ok, that might just be a matter of interpretation, as all ADHD drugs are used as 'study aids'). It has an interesting structure, with the closest known drugs being aminorex and 4-mar - the latter also being a rare occurrence these days and is said to have some special qualities. Urban myth or not?
I am diagnosed with adult ADD and initially got Concerta 18mg, then 36mg but had pronounced side effects, physical stimulation, strong sense of tension and forced focus.. d-amphetamine is better, yet worse when it comes to hangover / problems to get up in the morning, sometimes it is worse than other times.. MPH in contrast has a strong rebound which the amph lacks. Elvanse/Lisdexamph is mostly the same but with a different pharmacokinetic profile, indeed causes less hangover but it's hard to predict, on some days I am fine with one 20mg in the morning, other days I feel like I need three during the day only to realize that two would have been enough. So I am taking 20-40mg/d now.
Yeah, bupropion. A friend was on that for ADHD too and found it a good aid, yet she was taking it alongside crazy dosages of d-amph. I was on it myself but before the ADD diagnosis, yet I found it to rather increase restlessness.
Never tried strattera (atomoxetine) but the close cousin reboxetine, which has in the meantime been withdrawn from market as useless, which is exactly what it was. Created some false energy, worsened impulsivity, anxiety and tension and raised heartbeat but nothing usable. Atomoxetine has been found to be a NMDA antagonist next to its NRI properties, I can well imagine that any benefit some get from it might come from that route..