trainman04
Bluelighter
- Joined
- Dec 18, 2017
- Messages
- 189
On Wikipedia it says the mechanism of Metyrapone is:
So it increases Androstenedione and decreases cortisol? If I had an Overactive CRF-1 would this be it for me?
https://en.wikipedia.org/wiki/MetyraponeMetyrapone blocks cortisol synthesis[1] by reversibly inhibiting steroid 11β-hydroxylase. This stimulates ACTH secretion, which in turn increases plasma 11-deoxycortisol levels.
So it increases Androstenedione and decreases cortisol? If I had an Overactive CRF-1 would this be it for me?