Let me tell you all a little story about immodium....im a recovering heroin, methadone, Benzo addict who decided to use high dose immodium loperamide 3 years ago to alleviate my fentanyl heroin withdrawal. The first night I took 180mg. In the middle of the night I woke up in a weird tunnel vision to my parents slapping me in the face, I thought I had a seizure but it turns out it was something MUCH scarier.. The second day, i took my next dose, this time 140mg. I was watching t.v. and next thing you know I was waking up to tunnel vision again. Long story short after one week i cut my dose to 20 to 30mg a day for next 3 years. 3 months ago I started to feel a pressure in the center of my chest pushing outward, I thought it was anxiety. It got so bad I checked myself into an emergency room. Smartest decision ever. WELL let's just say my heart went into arythmia 5 times in 2 days, I code blued 6 times, woke up to chest compressions and paddles each time. Each time I woke up it felt the same way it did 3 years ago when I would wake up to tunnel vision and blackness all around. I had a temporary pace maker put in for 12 days to get my heart back in rhythm while they hit me with nalaxone 6 times. Which by the way, each time I was nalaxoned, it felt like they lit me on fire. Worse then anytime I was nalaxoned while on dope or methadone. They couldn't give me meds to help wtdrawal bc my heart rate was beating out of rhythm and at 36bpm. It turn out that long term use wt low doses or short term use with high dose of loperamide will cause an increased QTC interval, which will cause arythmia and death instantly and at any point without notice. Emphasis on without notice. I was lucky my heart didn't stop 3 years ago with the high dose bc the doctors said I had arthmias and not seizures then. It seems GOD IS giving me another chance. I'm clean 3 months now. If anyone thinks immodium is the way to go for wtdrawal from other opiates, just remember this story. God bless!!!!!!! Btw, my immodium withdrawal is still in my legs 3 months later and 6 nalaoxone shots later.. peace