• 💊 OTHER DRUGS 💊 Welcome Guest
    Posting Rules Bluelight Rules
    Notable Threads 1 Notable Threads 2
    Dangerous Combos Addiction Support
    Emergency Services Benzo Guide v.1
    Addiction Stories Scary Case Studies
    Biology, Pharmacology & Drugs 101
  • Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

Opioids Kratom Mega Thread v. 5

7nos-SS373dOH said:
Yeah but nobody can deny that is has a "High potential for physical dependency."

The thing is, regardless of it being a safer alternative to h, it still is a mind altering substance and causes physical and psychological dependency. It does not surprise me in the least bit that kratom is going to be scheduled, and it shouldn't surprise anyone else.
Click to expand...

My point was just that kratom is a clear, safe substitute to other, far more dangerous and addictive pharmaceutical opiate/ opioid pain medications. It's method of action is known (the fact that it hits delta opioid receptors is part of what makes it safer) and it obviously works for pain, so how can a non-scientific body like the DEA flippantly claim that it has no medicinal value? It's absurd.
 
JustferFun said:
My point was just that kratom is a clear, safe substitute to other, far more dangerous and addictive pharmaceutical opiate/ opioid pain medications. It's method of action is known (the fact that it hits delta opioid receptors is part of what makes it safer) and it obviously works for pain, so how can a non-scientific body like the DEA flippantly claim that it has no medicinal value? It's absurd.
Click to expand...
Well schedule 1 drugs don't mean there is zero medical use for them, it just means they don't have an ACCEPTED medical use.. There is a difference, especially when most people of authority are close minded or corrupt.

I personally think kratom should be schedule 3 or 4, basically meaning that you should be able to get a prescription written for you by a doctor and that it is less addictive than drugs that are schedule 1 or 2. But pharmaceutical profits were definetely taken into consideration, when it got scheduled!
 
I think it should be regulated to some degree(purity, source, etc), but certainly not scheduled. It should be over the counter in the nutrition aisle at like GNC or the pharmacy.
Think of all of the OTC stuff that has the potential to be much more harmful both physically and psychologically(addiction)...

You can't overdose on it and it doesn't really impair you, at least not like alcohol, weed, or real opiates.
 
There have been batches, that were indeed able to put you down to bed for a few hours feeling sick if you dosed too much. But it is correct, that the likelihood of dying from a Kratom OD is significantly (ld50 was never tested? even if was tested for the mitragynine derivates, then it would be difficult to estimate the ld50 of the substance orchestration, that Kratom is) lower than for opiates and alcohol.

Weed is still a little saver physically while mentally it is more dangerous when abused ime.
 
Hello, I looked on the internet for Kratom but there are so many different kinds. What is the best kind to get?
 
Goldenbluebell said:
Hello, I looked on the internet for Kratom but there are so many different kinds. What is the best kind to get?
Click to expand...

In my opinion, the strains are more similar than they are different and alkaloid content/ variety can vary batch to batch. If you're stuck, just pick one and work from there. Bali is more relaxing/ sedating and Maeng Da is the most energizing. Then there's everything in between. There's a lot of info on the interwebs. I believe the main differences are between the "white vein", "green vein" and "red vein" varieties.

I tend to go with Maeng Da but I'll take any of them, really.
 
Ok so I'm a lil naïve when it comes to this Krantom..... I looked it up and it's seems to be an opium plant.... Can someone explain to me how to get this and what exactly it is??? Just curious is all....
 
Dawn86Tn said:
Ok so I'm a lil naïve when it comes to this Krantom..... I looked it up and it's seems to be an opium plant.... Can someone explain to me how to get this and what exactly it is??? Just curious is all....
Click to expand...

It's a tree from southeast Asia. It's related to the coffee plant. It's not opium. You can order it online from a ton of different places and even some headshops/ smoke/ vape shops carry it. However, it's going to be illegal at the end of September, so you might as well forget about it at this point.
 
Dawn86Tn said:
Ok so I'm a lil naïve when it comes to this Krantom..... I looked it up and it's seems to be an opium plant.... Can someone explain to me how to get this and what exactly it is??? Just curious is all....
Click to expand...

It is the leaves of the tree Mitragyna Speciosa, it contains many alkaloids, most notable Mitragynine and 7-hydroxymitragynine. These substances do activate opioid receptors, however they would be consodered opiOIDs, not opiates, as the don't occur in the poppy plant and aren't derived from poppy plant alkaloids. Has always been legal in the U.S. but not for long, as the DEA has decided to emergency schedule it as a class 1 drug. A shame really, as it's a pretty mild source of natural opioids, with a ceiling effect and no respiratory depression, making for a great alternative to street/pharmaceutical opioids. It is addictive, but less so than strong opioids, and can serve as a maintenance. The main thing to worry about is vendors adulterating it woth other chemicals. It's been offered online for sale as far back as 2005, but recently it became more popular, being offered at head shops and even gas stations, hence the DEA getting involved.
 
RDP89 said:
It is the leaves of the tree Mitragyna Speciosa, it contains many alkaloids, most notable Mitragynine and 7-hydroxymitragynine. These substances do activate opioid receptors, however they would be consodered opiOIDs, not opiates, as the don't occur in the poppy plant and aren't derived from poppy plant alkaloids. Has always been legal in the U.S. but not for long, as the DEA has decided to emergency schedule it as a class 1 drug. A shame really, as it's a pretty mild source of natural opioids, with a ceiling effect and no respiratory depression, making for a great alternative to street/pharmaceutical opioids. It is addictive, but less so than strong opioids, and can serve as a maintenance. The main thing to worry about is vendors adulterating it woth other chemicals. It's been offered online for sale as far back as 2005, but recently it became more popular, being offered at head shops and even gas stations, hence the DEA getting involved.
Click to expand...

Not trying to be nit picky here, but kratom doesn't contain any opioids. That's a common misconception. Kratom's alkaloids do bind with some of the same receptors as opiates but it's only a small subset of receptors. The kratom alkaloids could be better thought of as being like endorphins that loosely stimulate some of the opiate receptors. The method of action is distinct from opioids and it's the reason that kratom is safer (i.e. no substantial respiratory depression, if any) and much less addictive than opiates/ opioids.
 
RDP89 said:
It is the leaves of the tree Mitragyna Speciosa, it contains many alkaloids, most notable Mitragynine and 7-hydroxymitragynine. These substances do activate opioid receptors, however they would be consodered opiOIDs, not opiates, as the don't occur in the poppy plant and aren't derived from poppy plant alkaloids. Has always been legal in the U.S. but not for long, as the DEA has decided to emergency schedule it as a class 1 drug. A shame really, as it's a pretty mild source of natural opioids, with a ceiling effect and no respiratory depression, making for a great alternative to street/pharmaceutical opioids. It is addictive, but less so than strong opioids, and can serve as a maintenance. The main thing to worry about is vendors adulterating it woth other chemicals. It's been offered online for sale as far back as 2005, but recently it became more popular, being offered at head shops and even gas stations, hence the DEA getting involved.
Click to expand...
Thank you!!! Maybe I have a few friends in head shops maybe they still carry it or can get some for me!!!
 
JustferFun said:
It's a tree from southeast Asia. It's related to the coffee plant. It's not opium. You can order it online from a ton of different places and even some headshops/ smoke/ vape shops carry it. However, it's going to be illegal at the end of September, so you might as well forget about it at this point.
Click to expand...
Or stock while u still can. Lol. How often will u come across a plant that acts like an opiod?
 
JustferFun said:
Not trying to be nit picky here, but kratom doesn't contain any opioids. That's a common misconception. Kratom's alkaloids do bind with some of the same receptors as opiates but it's only a small subset of receptors. The kratom alkaloids could be better thought of as being like endorphins that loosely stimulate some of the opiate receptors. The method of action is distinct from opioids and it's the reason that kratom is safer (i.e. no substantial respiratory depression, if any) and much less addictive than opiates/ opioids.
Click to expand...

This is completely wrong. Kratom is a mu and kappa opioid receptor agonist. This has been experimentally demonstrated many times. Its true that it doesn't elicit substantial respiratory depression though.
 
Slow_Mobius said:
This is completely wrong. Kratom is a mu and kappa opioid receptor agonist. This has been experimentally demonstrated many times. Its true that it doesn't elicit substantial respiratory depression though.
Click to expand...

OK, you're right but I might not be completely wrong. There may be some room for interpretation. Is salvia generally considered an opioid because it acts on kappa opioid receptors? Thinking about it, in all honesty, I think I'm just trying to distance kratom from the term opioid because it has a negative connotation with the general public.
 
JustferFun said:
OK, you're right but I might not be completely wrong. There may be some room for interpretation. Is salvia generally considered an opioid because it acts on kappa opioid receptors? Thinking about it, in all honesty, I think I'm just trying to distance kratom from the term opioid because it has a negative connotation with the general public.
Click to expand...

Salvia is a kappa opioid agonist. Kratom primarily acts on mu opioid receptors just like classical opioids. I think trying to distance from a term opioid when it's mechanism of action is almosthe same will ive people the wrong impression--especially when you say it outright isn't an opioid.

I would highlight the research that has shown in animal models that kratom simply isn't addictive. It's hard to get mice addicted to it in self administering tests, and it can take around 6 times longer to develop tolerance than opiates. There are mechanisms we don't understand, and further reseach could provide great insight into nociceptiona and maybe novel mechanisms for developing/preventing tolerance to mu opioid agonists.
 
I just called my congressman/respresentative's office today and spoke with one of my representative's staff members about Kratom and shared the entire story and he was extremely polite and said he would mail me back a response.

Call (202) 224-3121 and ask for your representative's number and they'll ask you for your zip code and then tell them to sign the Pocan/Salmon Dear Colleague Letter (make sure to spell out the name of the letter so they don't get it wrong) and how 130,000 people have already signed a petition to the White House to stop Kratom's ban and if you want you can share your story and tell why it is so wrong that they are trying to ban Kratom.

He said I wasn't the first person in my area to call about this issue.

THIS IS THE FIRST THING LIKE THIS I'VE EVER DONE IN MY LIFE!!

It felt good to do, regardless of whether or not I make an impact.

PLEASE EVERYONE WHO READS THIS PHONE YOUR REPRESENTATIVE ASAP!!!

People are saying it must be done by 4:30PM so you have HALF AN HOUR Eastern Standard Time or I guess 2-3 hours if you are on the West Coast depending on your area.

DON"T DELAY!!!

(But even if you DO miss that deadline I'd suggest you KEEP calling!!!)

WE MIGHT be able to make a difference!!
 
Last edited:
You must log in or register to reply here.
Top