So i like to think that I'm an aspiring psychonaut. I've tried 25i-nbome a couple times, LSD-25 a couple times, and recently got my hands on some 1p-lsd(love it!). I realize that these are all closely related in term of structure and effect(generally I think) and I wanna know what other kinds of substances people think is necessary/helpful to really explore the mind and all things psychedelic. I know many praise tryptamines and such, so I was thinking of trying 4-act-dmt. I've also been reading about dissociatives and they seem interesting but not really sure what's out there and what the whole appeal is. Any feed back would be greatly appreciated. This is only my second post on here so sorry for any mistakes!
Officially, Bluelight has a rule against "what should I take" threads, but I'll still try to shed some light:
The "classic" psychedelics primarily act on the serotonin receptor 5HT2A, with the two main groups being the Phenethylamines (e.g. Mescaline, the DOx series, the 2C-x series and the NBOMe's) and the Tryptamines (e.g. Ayahuasca/DMT, shrooms, various 4-HO and 5-MeO substituted tryptamines). LSD and the other lysergamides are often considered "conformationally constrained" tryptamines.
Anyway, 4-AcO-DMT ("Psilacetin") is closest to shrooms ("Psilocybin" / 4-PO-DMT), as both end up being converted into Psilocin (4-HO-DMT). However, people report some subtle differences between 4-AcO and the natural product, possibly due to them entering the brain at different rates and/or 4-AcO potentially being mildly active on its own whereas Psilocybin cannot cross into the brain before being converted to Psilocin.
Likewise, 1p-LSD mainly seems to act as a prodrug for LSD, as does ALD-52. ETH-LAD and AL-LAD, on the other hand, have more of a character of their own, with more intense visuals in relation to the mental effects. Between the two, AL-LAD seems like the more easygoing one, with some users also reporting physical discomfort - including nausea - from ETH. Still, so far I actually prefer ETH-LAD, but they are both amazing substances. Note that ETH usually comes on 100 µg blotters and is more potent - at least in the visual department - than LSD, whereas a single tab of AL-LAD normally contains 150 µg of material to compensate for its lower potency.