TheBlackPirate
Bluelighter
- Joined
- Dec 16, 2015
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- 680
I was going through medical journals recently and noticed something new recently about PCP in comparison with classical psychedelics. Classical psychedelics are associated with reductions in violence and in the same situation PCP is associated with increases in violent acts.
I realize PCP users suffer from perma-tolerance and animal models demonstrate PCP causes brain damage (unconfirmed in humans). Talking about those purported effects of PCP isn't why I created this thread.
My thoughts are perhaps differences in the experience and/or pharmacological action causes the variation. Speaking of the medical journals here they are:
Obviously larger studies and further research is necessary. With the evidence available, lets discuss how classical psychedelics are associated with decreases in this behavior while PCP is associated with increased partner violence. How are classical psychedelics different than PCP? Are the experiences different and/or is this a difference in pharmacological mechanism of action?
I realize PCP users suffer from perma-tolerance and animal models demonstrate PCP causes brain damage (unconfirmed in humans). Talking about those purported effects of PCP isn't why I created this thread.
My thoughts are perhaps differences in the experience and/or pharmacological action causes the variation. Speaking of the medical journals here they are:
https://www.ncbi.nlm.nih.gov/pubmed/27097733/Medical Journal of Psychopharmacology said:J Psychopharmacol. 2016 Apr 19. pii: 0269881116642538. [Epub ahead of print]
Hallucinogen use and intimate partner violence: Prospective evidence consistent with protective effects among men with histories of problematic substance use.
Walsh Z1, Hendricks PS2, Smith S3, Kosson DS3, Thiessen MS4, Lucas P5, Swogger MT6.
Author information
1Department of Psychology, University of British Columbia, Kelowna, BC, Canada [email protected].
2School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
3Department of Psychology, Rosalind Franklin University of Medicine and Science, Chicago, IL, USA.
4Department of Psychology, University of British Columbia, Kelowna, BC, Canada.
5Centre for Addictions Research of BC, University of Victoria, Victoria, BC, Canada.
6University of Rochester Medical Center, Rochester, NY, USA.
Abstract
Evidence suggests that hallucinogens may have therapeutic potential for addressing a variety of problem behaviors related to the externalizing spectrum of psychopathology, such as substance misuse and criminality. Intimate partner violence (IPV) is a prevalent form of criminal violence that is related to externalizing pathology. However, the association between hallucinogen use and IPV has not been comprehensively examined. In this prospective study, we examined the association between IPV and naturalistic hallucinogen use among 302 inmates at a US county jail. Cox regression analyses indicated that hallucinogen use predicted reduced arrest for IPV independently (β=-0.54,SE=0.20, χ2=7.19, exp(B)=0.58,p<0.01) and after accounting for covariates (β=-0.48,SE=0.23, χ2=4.44, exp(B)=0.62,p<0.05). These results add to a growing literature suggesting distinct therapeutic potential for hallucinogens to assist in the attenuation of problematic behavior.
https://www.ncbi.nlm.nih.gov/pubmed/23815422/Journal of Addictive Diseases said:J Addict Dis. 2013;32(2):150-7. doi: 10.1080/10550887.2013.797279.
The association between phencyclidine use and partner violence: an initial examination.
Crane CA1, Easton CJ, Devine S.
Author information
1Research Institute on Addictions, University at Buffalo, SUNY, Buffalo, NY 14203, USA. [email protected]
Abstract
The association between phencyclidine (PCP) use and violent behavior is unclear. The current investigation evaluated the association between PCP addiction and intimate partner violence, a specific violent behavior, using the substance abuse evaluations of 109 PCP, 81 cannabis, and 97 polysubstance (alcohol and cannabis) abusing offenders. Relative to both comparison groups, PCP users were more likely to receive inpatient referrals, have a significant legal history, and have perpetrated past-year general and intimate partner violence. Data suggest that PCP use may be associated with greater violence perpetration than cannabis use alone or in conjunction with problematic alcohol use.
Obviously larger studies and further research is necessary. With the evidence available, lets discuss how classical psychedelics are associated with decreases in this behavior while PCP is associated with increased partner violence. How are classical psychedelics different than PCP? Are the experiences different and/or is this a difference in pharmacological mechanism of action?