Is RLS one of the early symptoms of morphine withdrawal? I dosed in the early afternoon and hadn't dose again before bed. In the middle of the night I had the worst leg pain.
ABSOLUTELY. I never really got rls during withdrawal until I was wding from morphine. Kept me up all night and was awful.
Also what is considered a 'high dose' (not therapeutic) of instant release morphine to take in 'one go'?
Does codeine add to the amount of actual morphine you take? 200mg oral codeine is equal to 30mg oral morphine... So if you took 50mg morphine and 200mg codeine, would you technically be taking 80mg morphine?
A small amount does get metabolized into morphine, but it varies based on your liver enzymes (specifically cyp2d6 I believe, but don't quote me on that). Anyway, I think on average it's like 10%. You can take both together, I always did in the form of poppy seed tea, but just be careful. It won't do a whole lot other than make the opiate effect srronger, but codeine and morphine feel similar apart from strength IMO, maybe others will disagree or I just metabolize codeine well though, I've never thought it to be as weak as others make it out to be. Not for pain, anyway. It's not that euphoric.
Does Morphine cause palpitations and a fast heart rate?
No, but anxiety can. I often used to get this because I was worried I might be pushing the OD boundary, it was just anxiety though. Unless a paradoxical reaction is possible? Idk though, I've never heard of that with morphine although its happened to me on benzos. Anxiety is still my guess though, very common when doing drugs, especially when you're not yet used to them.
Is going from abusing codeine to pure morphine a big opioid 'jump'?
Well, I usually abused both at the same time, or at least during the same time period, so I guess I couldn't really tell you. Morphine is significantly stronger than codeine for most people, I definitely feel the difference but its not that huge to me. Morphine doesn't have a ceiling like codeine does though, so there's a lot more abuse potential. Never nodded on codeine alone either, but often on morphine (hence the username).
When having an opioid addiction should you be using laxative therapy daily or only as needed?
I never used it during my 6 month fling with various opiates and when I finally detoxed for real, TMI but I took the biggest shit ever. It literally clogged my pipes. Like, the ones attached to the toilet. So its probably a good idea. Morphine is one of the worst offenders for me as far as constipation goes, I'm sure if I actually had the money to use more I would've run into bigger problems but even with plenty of mini "breaks" I still had issues and was felt very bloated all the time so watch out. People recommend stool softeners over stimulant laxatives and probably for very good reason. I tried senosides once and it was AWFUL. I've never even had opiate WD diarrhea that bad before, only thing I could compare it to was when I had food poisoning one time, minus the projectile vomiting.
I get funny tingling feelings in my legs when the morphine kicks in - is that part of the 'high'?