Wow, two threads at once.
About three hours after MDMA is taken, dopamine metabolites make their way into serotonin receptors.
This destroys axons and SERT expression.
Anything that increases dopamine, is likely increasing this toxicity.
I HIGHLY recommend against this combo, despite the additional rush it provides.
Most experienced users agree that it makes the 'comedown' harder, and it only belongs at the END of the MDMA trip.
If taken before the comedown begins, it can fuck up the entire roll.
MDMA damages striatal dopamine neurons through nearby serotonin activity.
While this doesn't happen in all users, it is certainly seen in METH or amphetamine users.
This is an important clinical finding since it correlates with severity of depression in former METH users.
Combining speed and MDMA likely increases striatal dopamine death, which directly impacts your primary reward circuitry.
And it also kills off more serotonin axons in the higher brain, meaning you will 'lose the magic' much sooner.
And if you are a regular cannabis user, you have just increased the likelihood of major psychological problems from MDMA.
Mixing drugs is pretty risky.
And this combo is KNOWN to cause more damage.
So why do it?
If you need a speedy lift after rolling, try caffeine.
Or work out.
I agree with the recommendation about dexedrine.
METH amphetamine is far more toxic than dexedrine.
Both are toxic and dirty with regular use, but METH delivers a MUCH faster and deeper thrust into the brain.
It isn't worth it, and you have TWO experienced drug users here recommending 'dexies' over street shit.
And it is SHIT.
I would listen.
I'm on adderall xr 20 mgs everyday .. and I don't like to take it or a full dose of it ( as I can bearly stay awake without adderall xr in the am sadly..need naps not like survival lol) anyway I take that use to love addys... never ever do I want to mix it...
On the days where I get real molly or mdma or e I don't take it or I take a small amount ( yes I actually pour out a speed drug just dump half this capsule..) Just for MDMA to be better than if mixed.
you certainly can mix them though I'd advise being careful of course but I wouldn't do it if I had the choice..
Hi, im new to this bluelight, can you tell me what adderal is? Is it speed from a doc?
Wow, two threads at once.
About three hours after MDMA is taken, dopamine metabolites make their way into serotonin receptors.
This destroys axons and SERT expression.
Anything that increases dopamine, is likely increasing this toxicity.
I HIGHLY recommend against this combo, despite the additional rush it provides.
Most experienced users agree that it makes the 'comedown' harder, and it only belongs at the END of the MDMA trip.
If taken before the comedown begins, it can fuck up the entire roll.
MDMA damages striatal dopamine neurons through nearby serotonin activity.
While this doesn't happen in all users, it is certainly seen in METH or amphetamine users.
This is an important clinical finding since it correlates with severity of depression in former METH users.
Combining speed and MDMA likely increases striatal dopamine death, which directly impacts your primary reward circuitry.
And it also kills off more serotonin axons in the higher brain, meaning you will 'lose the magic' much sooner.
And if you are a regular cannabis user, you have just increased the likelihood of major psychological problems from MDMA.
Mixing drugs is pretty risky.
And this combo is KNOWN to cause more damage.
So why do it?
If you need a speedy lift after rolling, try caffeine.
Or work out.
I agree with the recommendation about dexedrine.
METH amphetamine is far more toxic than dexedrine.
Both are toxic and dirty with regular use, but METH delivers a MUCH faster and deeper thrust into the brain.
It isn't worth it, and you have TWO experienced drug users here recommending 'dexies' over street shit.
And it is SHIT.
I would listen.