Raaaaargh! Wounded. Had an early finish yesterday so thought I'd make the most of it and do in the 2 x 25-I-NBOMe blotters ( 550ug HPBCD complexed apiece / 1.1mg total ) I've been waiting to do all week. Forgot I'd taken 5mg Mirtazipine for the first time in months ( Yup. Stupid, I know! ) the night before to help me sleep with an ear infection, the damn thing almost completely blocked it. There was just enough there as a threshold dose to know how a properly active dose is likely gonna be. Even with the barely there, just-enough-to-be-a-little-tease visuals the CEVs were quite unique, fully realised in their solidity, fully 3-dimensional / multi-dimensional, geometric, kinda fractal-like and highly dynamic. They were familiar to me, but unlike anything I've seen on LSD / shrooms / MDA etc. Decent music with a psychedelic edge sounded just incredible, Shpongle and Eat Static nearly tore my head off at times with the stuff going on. Not heard such width and depth for a long, long time.
Questions:
1) Standard advice is leave up to a month between Serotonergics of any description but past experience tells me I could / can still get pretty full effects after around 7 days with stimmy psyches like aMT / 5-IT / 6-APB / MDMA etc. It's extended periods of once weekly use that tend to become more noticeably depleting. Is the tolerance issue unusually problematic with this chem in particular, or would that likely apply here?
2) Is it the case that receptors were properly blocked by the Mirtazipine, not exposed as such, and would therefore come available as soon as it's been eliminated? Can they be taken out of the tolerance equation, or is that just wishful thinking based on my limited and incomplete understanding of the pharmacology.
3) Are they all so uniformly cross-tolerant that there's no point trying the 25-B or C NBOMe any sooner either?
4) Does the fact that ~3mg Mirtazipine ( Amount likely remaining from 5mg initial dose after 18 hours ) mostly blocked 1.1mg 25-I-NBOME tell us anything about the state of my receptors / brain chemistry?
TL;DR : How soon could I expect to be able to take B, C or I again and still get pretty full effects?