I DOUBT it if its d amph/adderall and Suboxone dude, neither one of them does anything noticeable to serotonin neurons but ofcourse genetics play a role in drugs activation of Serotonin. Mao a gene could make a theoretical serotonin boosting effect from amphetamine more potent but I doubt it.
MDMA alone or Meth do not cause Serotonin syndrome in non ODs in most people so I assume the combination of D amph and a non tramadol super synthetic opiate do not.
Do opiates even act on Serotonin? They are euphoric not boring Its not 5 htp lol.
With Xanax too, I know little about the safety of the combo of all three in general, but that would definitely block any chance of SS symptoms anyway assuming its not just fucking dangerous in general to take all THREE euphoriants daily just to face the day.
Do you actually have Anhedonia/Butthurt/and anxiety all at once to need stims/opiates/xanax lol.