Gabapentinoids Why Does Caffeine Potentiate Gabapentin So Much?

[ChemicallyEnhanced]

I've heard people recommending taking caffeine with Gabapentin to potentiate it, but I was sceptical because I didn't see how that would logically make sense,
Anyway, I've tried it a few times now and WOW, it makes a HUGE difference.

 

[JackARoe]

I never drink coffee if I take it late afternoon. And I usually do it late afternoon. But my method of stagger is 600 mgs every 45 minutes and within there have a shot of apple cider vinegar and slam a large Coca Cola. Peanuts and food nibbles to chase it.

But yes, caffeine can potentiate a lot of things.

 

[Coffeeshroom]

Well that sounds promising in a way if there is any truth to it or if it only applies to certain individuals

 

[Snafu in the Void]

People say caffeine potentiates a lot of things. Opioids, kratom, amphetamines... I ever heard it helps you metabolize LSD and come up quicker.

I don't know... I think placebo may be present here. Take stimulants... Is it actually potentiating it or is it just causing additional stimulation making you think it's a stronger effect.

What really is potentiation? Increasing the effects of one drug? Or increasing the total effect combined? Does that even make sense to anyone?

 

[JackARoe]

^ Yeah it could be I am just more awake to enjoy an effect instead of sleepy. I know caffeine is added to aspirin to enhance the pain killing effect in some preparations. However I always added some regular caffeine tea to my poppy tea back in the day to add that little extra glow. I agree it could all be mental.

 

[Dextro .45]

Coffee a few hours after taking 1.5/2g of Phenibut is wonderful

might carry over to Gabapentin

 

[GetMeOutOfThisCRAP]

I doubt there is any truth to this.. caffeine works well with anything drug wise.

I like my purdue and adderall with starbucks.