RCs Which RCs to avoid when on an SSRI?

[Slc6a4]

hi everybody

I'm on escitalopram and am really happy with it, at the other hand I'm dependent on it not to fall into a deep depression. So I don't want to stop it.

Lately I am interested in RCs again and I wonder which ones are serotonergic and should be avoided to prevent serotonin syndrome?

I have been out of the 'scene' for a few years but want to do some experimenting, but in the safest possible way.

thanks

 

[darvocet21]

If you suffer from major depression probably shouldn't be taking hallucinogens or RCs but if you want to then to be on the safe side, avoid SSRIs when taking RCs

 

[Slc6a4]

If you suffer from major depression probably shouldn't be taking hallucinogens or RCs but if you want to then to be on the safe side, avoid SSRIs when taking RCs

thanks for your view. I was thinking of some dopaminergics maybe, I am definitely avoiding hallucinogens and serotonergics, but with the RCs i have too little knowledge to know what they actually do

 

[guy1234]

Certainly avoid any MAOI's such as AMT

Pretty much a fatal combination with SSRIs

 

[simstim]

I didn't have any issues with rc stimulants, psychedelics, or dissociatives in combination with citalopram. All worked as they should.

 

[simstim]

Avoid anything MDMA related. It won't work at all.

 

[simstim]

Benzos are fine too

 

[psynce of sound]

I would avoid RC Opioids, there is increasing evidence that Opioids can contribute to the occurrence of serotonin syndrome.

The following is a study into such.

Serotonin syndrome: fentanyl and selective serotonin reuptake inhibitor interactions - PubMed

Serotonin syndrome is a rare but potentially fatal adverse drug reaction associated with increased serotonergic activity in the central nervous system. It is characterized by a triad of symptoms, which include altered mental status, neuromuscular hyperactivity, and autonomic instability or...

pubmed.ncbi.nlm.nih.gov

 

[psynce of sound]

Pentylone et al are likely no go areas
The halogenated amphetamines and cathinones are likely no go as well.