Tianeptine completely ruined my phenibut experience today. Im thinking that the mu-opiate antagonism is responsible. I also have noted this with Kratom. At one point it actually caused me some rage which was completely unexpected.
okay mate but forgive me did you have a question? Other Drugs is specifically for people who need help with things, we have a social section for just blowing off steam but sounds more like you might want to direct this at the trip reports section, would you like me to move it there for you?
Tianeptine completely ruined my phenibut experience today. Im thinking that the mu-opiate antagonism is responsible. I also have noted this with Kratom. At one point it actually caused me some rage which was completely unexpected.
There is no antagonist properties from Phenibut as I know.
Tianeptine and Kratome are both mu opioid agonists. But both also affect serotonergic system and thats what probably caused you to feel shitty. They are combining fine with me.