- Dec 10, 2010
What would compel you to bring this up?
He's probably thinking of fluoroacetate, which completely shuts down the citric acid cycle in mitochondria. A lethal dose in humans is thought to be around 1-2 mg/kg. One possible route to 2C-EF would involve the use of fluoroacetic acid or an activated form like the anhydride to acylate 2,5-H, followed by reduction.