It's even broader than that, non-serotonergic psychedelics do stuff like this as well. Cannabinoids (especially THC) have an influence on the immune system. And salvia can be used to lessen the effects of inflammation too.Mind-blowingly amanzing, izo, thanks fro sharing !! Havent read past the abstract, but if it's 5HT2A-R activation alone that mediates the anti-inflammatory effect, then most psychedelics should share this property.