You should combine it with Tryptamines.
Could get very intense that way.
I always prefered ket or nitrous as a tryptamine booster.
The long effect of mxe made it abit riscy.
Also cannabis always made mxe very nice imo.
Esp the day after it could really bring the trip back.
When you take low doses of psychs and dissos you stretch your stash, go slow and work ypur weigh up like with anything. Mixing Tryptamines and Dissos is a common practice. Just be careful, its a great way to produce profound experiences.