N&PD Moderators: Skorpio | thegreenhand
"This study shows quite good efficacy compared to 60 mg of morphine," said Dr. Comfort. "It looks like an interesting compound with a dual mechanism of action with an opioid-like effect. In addition, it has a norepinephrine reuptake inhibition."
Additionally, total pain relief after 4 hours was higher with onset of action appearing more rapidly for patients in the tapentadol HCI 200-mg group compared with those in the morphine sulfate 60-mg group. The mean level of pain relief obtained with morphine sulfate 60 mg was between that achieved with tapentadol HCl 100 mg and 200 mg, they stated.
haribo1 said:Has anyone got a pointer to the patent? I'm fascinated by this stuff. It's almost a 'how simple can we make an opiate' challange. Are there any other opiates with a SINGLE ring system? Even demerol has 2...
haribo1 said:Has anyone got a pointer to the patent? I'm fascinated by this stuff. It's almost a 'how simple can we make an opiate' challange. Are there any other opiates with a SINGLE ring system? Even demerol has 2...