switched from phenibut to pregabalin

[scuba0095]

Hey here is the thing on and off all year i have been using phenibut. When i quit i get no phsyical w/d symptoms. But like kratom i just get that lingering ahadonia and dysphoria. I exercise meditate in therapy dbt cbt. Still that lack of interest in life just sucks.

I switched to pregabalin temporary because pehinbut tol got too high where two grams hardly did anything.

Anyone else do this? i was told they dont work on the same receptors but pregablin and benzos do take aaway the w/ds at least.

I will go back on phenibut to a low dose and keep trying to lower it slow to avoid that depression. Anyone try this? I got cbd oil not sure if it works or not.

 

[Speed King]

I have no idea. I use pregabalin and was thinking of switching to Phenibut.

 

[Hodor]

Pregabalin, despite the structural similarity to GABA (the major "calming" neurotransmitter in our nervous systems), doesn't seem to work on GABA receptors. Instead, it acts on certain calcium ion channels, which produces a psychological and physiological response that is in some ways rather similar to the one elicited by GABAergic drugs.

Phenibut, OTOH, acts on both the calcium channels as well as actual GABA-B receptors (similar to baclofen, except at much higher doses), which may give it a higher potential for abuse.