^^ How did your experimenting go? I'm very curious as I've been working on a similar experiment but with oxymorphone.
Now before I go any further, I apologize if this is de-railing your thread or off-topic. I was thinking maybe putting this in a oxymorph related thread, but to be honest I felt that it fit more into a nasal spray discussion.
It just seemed to me, that this thread was the best one I could find regarding nasal sprays & seemed to fit with what I was looking to discuss, just with a different substance.
So if I'm wrong I apologize.
I used a 1 fl oz pump nasal spray that screws off. The size doesn't really matter for my calc's though as I didn't fill it.
After spraying it to count the number of times it sprayed before emptying I came to the conclusion that each spray is approximately .1 cc.
As such I attempted to make a spray that was 3mg per CC.
I took 15mg of Opana IR, and proceeded to cold shake it in a oral syringe with 5 CC's of
Saline (Sodium Chloride .65% and Phenylcarbinol and Benzalkonium Chloride as preservatives)
After shaking/dissolving for a few minutes (I was inpatient) I then pushed the mixture through a cotton ball into the nasal spray bottle.
The spray seems to work fine as far as I can tell.
It's a very low dose approx .3mg per spray by my calculations, but seems to work.
I decided to use such a low dose as I didn't want to take a chance of being wrong in some way and getting to much/the whole thing in 1 spray.
The question I have is basically if my method/calculations are accurate or if I'm missing something.
Not having the solubility and such of oxymorphone handy, I'm basically curious as to whether or not the concentrations would be essentially equal per spray.
As by my (potentially flawed) math, if I dissolved 15mg in 5 CC's, that would be 3mg per CC.
If each spray is .1 CC's, that would be approx .3mg per spray.
This is assuming that the mixture would be equally distributed in the saline.
This may be an incorrect assumption. So if anyone has more information, tips, or other information correcting/helping me it would be greatly appreciated.
And again sorry if this isn't the appropriate place to post this. If there is somewhere more appropriate feel free to move/direct me to it.