I tried these and did not cause pain or discomfort. They actually work pretty good. These are smaller and break down to a finer powder than most so it might be just that you are not used to the finer powder. There are no fillers that would cause this nor are there anything in them to keep them from breaking down. I work in a lab and had them tested. They are right up there with Ms or As. It’s just a matter of preference really. I have been taking them for 15 years. This was the first time I ever saw these so I tested them. I snort them and all is well. Hope this helps