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Misc Seroque (and Other Meds) Veryl Suddenly Not Working

M

markanders7

Bluelighter
Joined
Jan 3, 2017
Messages
76
Although I am prescribed Serquel, I have an addiction to it (one of several presciption drugs I'm addicted to). I am prescribed 600mg/day which I obtained a prescription for by faking psychotic symptoms). I usually take either 900mg or 1200mg. This is usually enough - combined with my other meds - to have me nodding by evening.
I got my refill from the pharmacy today and took 600mg this afternoon. I Felt literally zero.
I have taken 2700mg now over the last 9 hours. I STILL feel very little. How is this possible?

I also took (all more than usual doses) - 300mg Cyclizine, 450mg Trazodone, 600mg Tramadol, during the 9 hours.

Normally a third of all of that would have me either very "stoned" or unconsious.

What's going on? Is this a normal experience?
 
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You're going to kill yourself if you keep upping your dose. The maximum daily dose of quetiapine is below 1000mg and as an antipsychotic it comes with nasty and potentially dangerous/lethal side effects that will increase with the dosage.
And 600mg of tramadol should be more than enough to give you a seizure, throw in some trazodone and cyclizine and your seizure threshold should decrease even more and your blood pressure will go down too.
 
At those doses, I would be concerned about developing serious nerological issues. Abusing antipsychotics and antidepressants is a really bad idea. And no, what youre experiencing is not a normal experience. I'm surprised youre still functional and not in the ER on that combo.

I don't think anyone is going to help you get high on crazy amounts of antidepressants and antipsychotics. I'm not trying to be patronizing, but I really think you should find a new psych specialist and be upfront about your current habits. Abusing these meds won't be sustainable for you.
 
How can you even like that shit,all the times i tried it in rehab it would make me feel like i had a fever,tired as hell,diZzy and it would block my nose i had to breathe from my mouth. Real nasty medication
 
As previously stated tramadol above 300 mg can cause seizures.

Seroquel by further antagonize 5 ht2a and 5 ht2c this may further increase the odds of having a seizure on tramadol.

Cyclizine 300-450 is enough to cause anticholinergic syndrome. Given such heroic doses of Seroquel it could have significant additional antagonism of the muscarinic acetylcholine receptors via the nor secondary metabolite.

Such high doses of tramadol and Seroquel could cause fainting upon standing by blocking alpha adrenic receptors which play a critical role in controlling blood pressure.

Due to the complex actions of seroquel , tramadol and trazadone on serotonin you could experience serotonin syndrome.
 
kleinerkiffer said:
You're going to kill yourself if you keep upping your dose. The maximum daily dose of quetiapine is below 1000mg and as an antipsychotic it comes with nasty and potentially dangerous/lethal side effects that will increase with the dosage.
And 600mg of tramadol should be more than enough to give you a seizure, throw in some trazodone and cyclizine and your seizure threshold should decrease even more and your blood pressure will go down too.
Click to expand...

I take Keppra for seizures anyway.
 
Maybe it is not the Quetiapine causing the high I'm missing. Could it be Cycizine? I do seem to have Anticholinergic Syndrome pretty much every day.
 
d1nach said:
I thought 300 mg is how much u always take of cyclizine.
Click to expand...

Sorry. I should have been more clear: I DO take 300mg Cyclizine, but in three doses, several hours appart. When I wrote the doses above I meant that I'd taken them all that evening (on top of my normal doses earlier in the day).

I think that was the mistake actually. I normally like stagger my doses. It must build up in my blood throughout the day, like an accumulative effect.
 
So you took a total of 600 mg of cyclizine in 24 hours ? I'm surprised you wherent hallucinating
 
I have been prescribed seroquel in the past as I actually needed it. I was prescribed 300mg daily maximum.

I was told its a safe drug as its pretty impossible to overdose on and die. I was told this because I did try to die after a bad break up by taking 50 100mg tablets.

I dont understand how you can get a nod or a high from this at all. I have had high doses and low doses but it deoends on your body weight as to what different doses do. Its a weird drug if little recreational value apart from when it begins working
, a short bit of time the floaty feeling is good then a knock out sleep and waking up to no crazy thoughts.

Maybe that dose was just wrong for what you expected. Less could be better for ya.
 
zephyr said:
I have been prescribed seroquel in the past as I actually needed it. I was prescribed 300mg daily maximum.

I was told its a safe drug as its pretty impossible to overdose on and die. I was told this because I did try to die after a bad break up by taking 50 100mg tablets.

I dont understand how you can get a nod or a high from this at all. I have had high doses and low doses but it deoends on your body weight as to what different doses do. Its a weird drug if little recreational value apart from when it begins working
, a short bit of time the floaty feeling is good then a knock out sleep and waking up to no crazy thoughts.

Maybe that dose was just wrong for what you expected. Less could be better for ya.
Click to expand...

I am actually prescribed it (600mg/day). I had quite a severe addiction to the RC 3-flourophenmetrazine (for people who don't know; it's a stimulant very very similar to amphetamine sulphate, only better as it was over 98% pure). It got to the point where I stopped eating and sleeping. I mostly "heard" people shouting my name and and seeing money and drugs; I spent up to 20 hours a day roaming the streets trying too pick up all these £1.00 coins and pills that dissappeared when I grabbed for them (basically my life was a Mario Bros game, gold coins and all).

My parents eventually got my psych doctor (whom I see for Borderline Personality Disorder) to hospitalize me. I have no idea where I was Volontary or not as I was so strung-out.

Because the 3-FM is not detectable and I vehemently insisted I was sober (I can't rememer why) and they eventually decided on the diagnosis as Schizoaffective Disorder. I was given Haldol and later it changed to Quetiapine. So I technically take it to combat stimulant-induced psychosis.

I have been clean of stimulants since then. I liked the warm and sleepy feel of quetiapine and how I could actually get a decent nights sleep, plus I gained weight on it (bad generally, but I was severly underweight; no grown man should weigh less than 100lbs). Taking a lot makes me sort of "nod", especially when combined with other meds. So I've been lying about having psychotic symptoms so my psych will keep increasing my dose. I'm gonna ask him to up it to 800mg at my next appointmant.

Last two nights my Seroquel is working. Maybe the really high dose had "delusions of sobriety". Like you get if you over-do the benzos.
 
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I tried to kill myself with a huge ammount of Seroquel too. I was in ICU in a coma for three days, I think was because I took a lot of Phenobarbital.
I'm around 125lb. What dose would be best in your opinion?
 
kleinerkiffer said:
You need to lower the dosage, not increase
You're harming your body and you already have a really low BP, decreasing it even further can kill you!
Click to expand...

You're right, I know. I don't know what it is but it's like I always have to have an addiction: I'm a recovering alcoholic, a recovering amphetamide addict, I'm bulimic, I've had problems with prescriptiom pills lately. I think I just hate being sober. Yep, thats it. I literally cannot stand being sober. All I can think of if I'm sober is anxiety and what can I do to help me get out of this?
I've had a really harrowing life, and the pills help me to forget it all and let me not think or feel.

Maybe I should go to therapy or NA or something.
 
Your never going to have enough seroquel because that is not what it is for. It is supposes to help people with bipolar or schizophrenia or unresponsive unipolar depression feel more appropiately their life instead of the crazy ups and downs.

For example i hve seen people with bipolar or schizophrenia take seroquel to become less numb and instead of detached hearing voices or not laughing at jokes .

If seroquel isnt helping you tune ìnto reality and instead just making you zone out you need to talk to your doctor about a new treatment
 
markanders7 said:
You're right, I know. I don't know what it is but it's like I always have to have an addiction: I'm a recovering alcoholic, a recovering amphetamide addict, I'm bulimic, I've had problems with prescriptiom pills lately. I think I just hate being sober. Yep, thats it. I literally cannot stand being sober. All I can think of if I'm sober is anxiety and what can I do to help me get out of this?
I've had a really harrowing life, and the pills help me to forget it all and let me not think or feel.

Maybe I should go to therapy or NA or something.
Click to expand...
Check out The Dark Side http://bluelight.org/vb/forums/47-The-Dark-Side and Sober Living http://bluelight.org/vb/forums/269-Sober-Living
 
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