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Question about CAS numbers.

A

Achten

Bluelighter
Joined
Jun 19, 2011
Messages
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Hi all,

Quick question about CAS numbers, specifically

Cas 7795-52-0. This appears to be (2R)-1-(1H-INDOL-3-YL)PROPAN-2-AMINE.

Cas 299-26-3. This appears to be (3-(2-AMINOPROPYL)INDOLE).

My chemistry knowledge is not sufficient to deduct this.

Are these identical? Different isomers of the same compound? Totally unrelated?

Thanks for your help !
 
Thanks already!

Can i pick your brain some more?

Suppose i would ingest them both, would there be a difference in perceived effects?

Apart from every experience being different since it's a psychedelic. You know what I mean.
 
Achten said:
Thanks already!

Can i pick your brain some more?

Suppose i would ingest them both, would there be a difference in perceived effects?

Apart from every experience being different since it's a psychedelic. You know what I mean.
Click to expand...
isomers of a different psychedelic compound will lead to extremely different effects this true for every form of drug. Some isomers are completely inactive. For example meth D isomer meth is super strong and is the stuff that get a person wired while the other isomer levo-meth can be used a nasal spray for decongestant.

This is true for all types of drugs.
 
Achten said:
Hi all,

Quick question about CAS numbers, specifically

Cas 7795-52-0. This appears to be (2R)-1-(1H-INDOL-3-YL)PROPAN-2-AMINE.

Cas 299-26-3. This appears to be (3-(2-AMINOPROPYL)INDOLE).
Click to expand...

The first compound is the R-isomer of AMT, the second is the racemate, i.e. a 50:50 mix of AMT's isomers (R and S).

Not sure if this is a case where all the activity resides in one isomer, or - as TripSitterNZ suggested - the two isomers have different effects.

Taking MDMA as an example of another drug that exerts both psychedelic and stimulating/empathogenic effects, it seems like S-MDMA is the more potent stimulant, while R-MDMA is responsible for the psychedelic and much of the empathogenic effect.
Apparently, the true "magic" of MDMA only shines through with the racemate, i.e. a mix of R- and S-MDMA.

The same may very well hold true for AMT.
 
Ok thanks ! I'll report back when I got to sample this R-isomer.
 
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