What do you think of supplements like l-tyrosine to assist with reducing tolerance?
I would have to look into it but I really doubt it.
Amphetamine tolerance and desensitization is more complex than your brain not having enough dopamine.
The problem is not really dopamine itsef, it has more to do with changes within the receptors. Some receptors will decrease the rate at which they release dopamine into the synapse, while others will decrease in numbers (downregulation), this all happens through multiple mechanisms which aren't even that well understood as far as I know.
I have seen some stuff about NMDA antagonists being able to prevent or even reverse (to a degree) amphetamine tolerance. I personally like to supplement with magnesium if I'm doing amphetamines, I think it's fairly weak as an nmda antagonist but it does have plenty of benefits.
There is some interesting stuff about NAC (N-acetylcysteine) as well, not sure how useful it would be in this case but I think it's worth researching. I mention it because it appears to be pretty safe and it's already used to treat other issues.
It's best to avoid taking random stuff (even "health supplements") as it could do more harm than good, always try to look for reliable sources.
Otherwise, if one can't find a way to prevent tolerance then the best thing to do is to avoid doing things that will for sure make it worse.
For instance, if you wish to continue to use amps therapeutically for a long time then don't take more than you have to, don't use them to get high and definitely don't binge on them for multiple days without sleep.
If you're using them recreationally then I think the only think that actually works is taking regular breaks. But even with breaks, if one gets into the habit of taking very high doses and going on binges sometimes low doses will never work again (at least not like they used to).