I started a thread with a poll to see how many people had taken bupe while addicted to kratom and whether they got PWD. One person claims to have gotten PWD, but also said that they only felt withdrawal for like 20 minutes and then fine. Personally I have taken bupe within an hour of dosing a full dose of kratom, when addicted to kratom, and felt nothing but relief (as in, the bupe did a better job than kratom, so when it displaced it, I felt better, not worse). I also have taken kratom while on bupe, and although the effect was very subtle, I did feel a bit of the kratom feeling, my thought it is has to do with the other, non-opioid receptor agonist effects of kratom alkaloids still working. Though I admit it could have been placebo. The effects I noticed were a slight increase in energy and a bit of that dizzy behind the eyes feeling that kratom gives.