Harm Reduction Poly-combo: Amphetamine-Mucuna-Syrian Rue-SJW?! ❄️☠️👍🤔🌈🌟

[uivodoet]

Should I do it in the name of science?

My ADHD meds (Adderall) didn't kick in at all today, so I took twice the dose, still feel ADHDish and lethargic as f#ck.
I want to just keep taking more of my ADHD meds until I feel clear in the head and fully operational, but I need to be smart and save some for the rest of the month...

I did not used to have this strange problem, my normal ADHD medicine
that dose would always have more or less the same effect.

Other circumstances/background info:
I have been taking some maca-root in the morning , and some mucuna in the evening...
I had fairly decent sleep, like 5-6 hours with vivid dreams, have been eating well.
I also took 1500 mg of Magnesium and a few table spoons of baking soda in a cup of water and
drank it just to make sure my body's PH-levels are ADHD medicine friendly.


So this is my brilliant idea!

( I know this is playing with fire but Im prepared to try it in the name of science.)

1.Take some additional Mucuna and hope that the L-dopa in there will boost my ADHD-meds.

2. Take a microdose of Syrian Rue, cause I heard it can severly boost amphetamines.
but if done in excess kill you from hypertension.

3.Take both Mucuna and microdose of Syrian-rue seeds.

4. Take both Mucuna and microdose of Syrian-rue seeds and add a dash of st.Johnsworth.
Just to make sure there is also some tiny additional serotogenic-effects to counter act the L-dopa's dopaminergic effect
from blocking the receptors and decreasing the serotonin? And then just hope that the MAOI harmala alkaloids from the Syrian Rue have some magical synergetic effect, that revives my corps.

Cause I need to finish an important project today and I can't afford to eat more ADHD-meds. (I know Serotonin syndrome and yada yada, but hypothetically I would really microdose the ethnobotanicals...)

Please answer fast, or my lack of impulse control due to dysfunctional ADHD meds, will force me to start experimenting right away.
If I can't be bothered to wait for some scientific down to earth feedback, Im just going to do it and keep you updated as I either wake the f... up and enjoy it. Or if I get hypertension and serotonin syndrome and die or call an ambulance or something...

Thanks for everything!

 

[Skorpio]

Don't mix maois and amp. Doubly don't take mucuna and an maoi, as the dopamine will have a temporary hypotensive effect that could mask toxicity from stimulant overdose, and then come back with a vengeance as dopamine gets cleared by other enzymes.

It is not advised to mix stimulants with maois. It is a worse idea to do so with a non-standardized plant maoi (as you lose the ability to dose precisely).

Finally it is even worse to add a plant into that mix that contains dopamine precursors and a pretty wide range of other actives at low levels (which could be rendered significant by mao inhibition).

Literally just add coffee or ephedrine from the drug store or do a shot of liquor, don't increase your dose via enzyme inhibition.

 

[uivodoet]

Don't mix maois and amp. Doubly don't take mucuna and an maoi, as the dopamine will have a temporary hypotensive effect that could mask toxicity from stimulant overdose, and then come back with a vengeance as dopamine gets cleared by other enzymes.

It is not advised to mix stimulants with maois. It is a worse idea to do so with a non-standardized plant maoi (as you lose the ability to dose precisely).

Finally it is even worse to add a plant into that mix that contains dopamine precursors and a pretty wide range of other actives at low levels (which could be rendered significant by mao inhibition).

Literally just add coffee or ephedrine from the drug store or do a shot of liquor, don't increase your dose via enzyme inhibition.

Good idea @Skorpio (thanks for your well informed and thoughtful answer, you are probably right).
I'll add some coffee and booze to the whole equation, ha ha ha!

Im thinking of just taking like 7 harmala seeds, and only a capsule of mucuna...
I know it's not adviced to mix MAOI's and stims, but it's also not advised to take stims...
And Nicotine is a MAOI, and no one is nagging about not mixing speed and cigarettes...
The most scetchy component would be my wild crafted SJW, probably going to leave that one out...
That the Harmala potentially could make the velvet bean (Mucuna) into a magical bean, sounds cool ASF!
But at such low doses Im sure it would only bring a very very subtle discomfort or just make the freaking amp do it's bloody job...

I have shitloads of benzos and pregabalin if I start to feel SS I'll just take a whole bunch of those, thats what they give you in the emergency room anyway. And If I get hypertension maybe popping a Cialis could work thats. originally a heart medicine to lower blood pressure...

I have a good feeling about this, stay tuned folks!


Edit-
The Seven Sages entered the temple...
A capsule of velvet bean made it's way into my coffee cup...
Let's see if this wakes the sleeping giant up...👁

 

[uivodoet]

@Skorpio
Just about to start zipping on the mucuna infused coffee now... Chewing the seven Harmala seeds made me feel a bit groovy like, I felt so much better right away, my handheld device looks more glowing, must be psychological/placebo?

Or Magic? They Harmala seeds are considered magical, powerful protective mojo type of stuff in the Middle East...
All well so far!

 

[Skorpio]

My issue isn't the combo, it's that you are doing it in plant form so you don't know dosages. Even with slow dosing effects can appear very quickly with slight increases due to dose response curves losing linearity with enzyme inhibition. You will probably be fine, but combos like this are flirting with negative outcomes.

 

[uivodoet]

Okay, more then an hour has passed, since I had consumed amp, and the ethno-botanicals.
I have been feeling great really relaxed, and now I have to sleep?

But I feel totally relaxed and sleep feels like something nice that I wanna do. I usually have insomnia and never really sleep...

Well Im still alive anyway, and the mix did not amplify the more adrenaline fuled flight or fight reflexes of
amp, but I felt more relaxed medicinal amp endorphin feeling. Very nice..

I have to sleep It just made me feel good in my whole body, and now I want to sleep,
but i all in a good very nice way... And yes the walls are kind of wavy,
now I have to get some proper rest!

Interesting experiment....
Thanks everyone!
ZZzzzzzzzzzzz

P.s. sorry for any misspelling I have to sleep!

 

[uivodoet]

My issue isn't the combo, it's that you are doing it in plant form so you don't know dosages. Even with slow dosing effects can appear very quickly with slight increases due to dose response curves losing linearity with enzyme inhibition. You will probably be fine, but combos like this are flirting with negative outcomes.

Hello @Skorpio!
Just to show that I survived (and again in the name of science) I'll give you or anyone who might be interested some closure. I know I was a bit foolish and over enthusiastic, but I was hoping that 7 Harmala seeds (a microdose) would re:animate the adderall/amp, and that the Mucuna would fill up my hypothetically depleted dopamine reserves.

As you foreshadowed, the outcome was unpredictable, the harmala seeds brought some glow to the experience, but did not really re:animate the Adderall/amp's energetic effect, and the Mucuna coffee, put me right to sleep like a baby.
So everything went reversed from my own hypothetical theories (so I was wrong but it made enough sense in my head at the time to make me give it a try!)

Then during sleep I had the strongest visions of vulgar ghosts partying in my apartment and voices in my head,
I woke up a few times, tried to get up and just shake it, but every time I closed my eyes I was back in ghost world.

So I ended up blessing the room and performing an improvised ritual exorcism.
Praying for their souls to go to heaven, sending them light and love.

And then I went back to bed and no more ghosts or trance-like visions just deep restful sleep.

And now I feel great and well rested for the first time in a long time! Feeling decent.

Anyway think Im just going to try and stay off the Adderall/Amp, give my body and mind a break and get my tolerance in order, maybe try using some agmatine to see if that can normalize my tolerance.

Cheerios and thanks for your feedback @Skorpio !

 

[Keif' Richards]

OP, I'm not claiming to have a full understanding of your situation, but you're painting a very clear and vivid picture of the route toward addiction and dependence upon stimulants. It's a more gradual and subtle process than people are often made to believe. Don't believe what you hear in the Lame-Stream-Media folks! My addiction to Opioids started in the same fashion. An extra dose here leads to diminished effects when I take the next dose, suddenly, the higher dose is my normal dose.

I would really stop and think about what you're doing. This is not a lecture in a typical sense. I want you to be able to take advantage of the benefits offered by stimulant therapy and you're going to encounter problems if you keep taking extra dosages like this.

 

[uivodoet]

OP, I'm not claiming to have a full understanding of your situation, but you're painting a very clear and vivid picture of the route toward addiction and dependence upon stimulants. It's a more gradual and subtle process than people are often made to believe. Don't believe what you hear in the Lame-Stream-Media folks! My addiction to Opioids started in the same fashion. An extra dose here leads to diminished effects when I take the next dose, suddenly, the higher dose is my normal dose.

I would really stop and think about what you're doing. This is not a lecture in a typical sense. I want you to be able to take advantage of the benefits offered by stimulant therapy and you're going to encounter problems if you keep taking extra dosages like this.

I think I might have some mild comorbid bipolar, but thanks for the lecture, your right. I just wish my medicine would have the same effect every day.

 

[Keif' Richards]

I think I might have some mild comorbid bipolar, but thanks for the lecture, your right. I just wish my medicine would have the same effect every day.

I know buddy. Please don't look at it as someone talking down to you. We are equals here and I just want you to have as much information as possible so you can proceed with all of this in mind. I say we are equals, because the majority of us have been through this. We all want drugs to give us the same blessed effect every time we use them, but addiction often leads us to make the wrong decisions and we often don't realize how wrong those decisions are until it is too late.

Just try to use your stimulants judiciously. Keep the dose regular and if you ever desire to get that "magic" back, the best way to do that is by skipping days or possible, going several days on a lower dose. Taking drugs like this consistently will inevitable lead to a dulling of the perceived effects of the drug. I know it sucks, but it's just the reality.