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Opiates "insensitivity"

farmacista

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Mar 8, 2013
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165
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italy
So between 2017 and 2018 for a year or so i used to snorted heroin ... then took a vacation of 2 or 3 weeks during which i was only on methadone ... then when i returned home heroin didn't worked for me anymore ... i didn't get any high out of it ... just maybe a mild relaxation and some physiological symptoms like difficulty urinating ... i tried snorting fentanyl (sublingual tablets directly from the pharmacy, no adulteration involved. i'm pharmacist myself and i just took it pretending it was selled) if I remember correctly about 5 or 6 200 mg tablets, one of them properly use and the rest snorted ... and nothing just the same thing ... so the high isn't there anymore just the abstinence is still there so i'm still on methadone ... and is nothing like an high tolerance is insensitivity, no response pure and simple ... in the last year i started injecting cocaine so i did inject heroin too sometimes ... i had a weak flash, in my legs, it seems for some moments like my legs won't let me stand anymore, and sometimes a buzz around the head, like a fizz or something ... just for a few seconds, and it's not a strong flash like cocaine, then again no heroin high just some relaxation, useful to counteract cocaine but nothing like an heroin high (i tried to use heroin alone to perceive more effects from it but nothing). So all of this is very unusual ... Have you ever heard anything like this ? Is happen to you or someone you know ? Apparently there's nothing in the medical literature ... I can't possibly be the only one XD Quality of heroin isn't an explanation either, my friend have the usual effects from it
 

MsDiz

Moderator: DS
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Mar 31, 2020
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4,209
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Ireland
So between 2017 and 2018 for a year or so i used to snorted heroin ... then took a vacation of 2 or 3 weeks during which i was only on methadone ... then when i returned home heroin didn't worked for me anymore ... i didn't get any high out of it ... just maybe a mild relaxation and some physiological symptoms like difficulty urinating ... i tried snorting fentanyl (sublingual tablets directly from the pharmacy, no adulteration involved. i'm pharmacist myself and i just took it pretending it was selled) if I remember correctly about 5 or 6 200 mg tablets, one of them properly use and the rest snorted ... and nothing just the same thing ... so the high isn't there anymore just the abstinence is still there so i'm still on methadone ... and is nothing like an high tolerance is insensitivity, no response pure and simple ... in the last year i started injecting cocaine so i did inject heroin too sometimes ... i had a weak flash, in my legs, it seems for some moments like my legs won't let me stand anymore, and sometimes a buzz around the head, like a fizz or something ... just for a few seconds, and it's not a strong flash like cocaine, then again no heroin high just some relaxation, useful to counteract cocaine but nothing like an heroin high (i tried to use heroin alone to perceive more effects from it but nothing). So all of this is very unusual ... Have you ever heard anything like this ? Is happen to you or someone you know ? Apparently there's nothing in the medical literature ... I can't possibly be the only one XD Quality of heroin isn't an explanation either, my friend have the usual effects from it
You took 1mg of fentanyl?!
 

farmacista

Bluelighter
Joined
Mar 8, 2013
Messages
165
Location
italy
Yes, sorry i made a mistake, they were Abstral 200 microgram tablets so yes 1 mg in total ... but I'm insensitive so ...anyway there are 800 mg tablets so it's a safe dosage ... but i didn't get high XD it's the most strangest thing
 

farmacista

Bluelighter
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Mar 8, 2013
Messages
165
Location
italy
Not long, less than a year, i did heroin before while on methadone and the high was normal so it's not related to that ... it's absurd really
 

MsDiz

Moderator: DS
Staff member
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Not long, less than a year, i did heroin before while on methadone and the high was normal so it's not related to that ... it's absurd really
I mean, before you have taken all of the above. How long has it been since you’ve had methadone? A week? 2 days?
 

farmacista

Bluelighter
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Mar 8, 2013
Messages
165
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italy
You mean before the fentanyl thing, it was about a year. And it was about six months I after started methadone that heroin stopped have effects on me ... and also there isn't a difference in heroin's effect if i skip a day of methadone before doing heroin
 

farmacista

Bluelighter
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Mar 8, 2013
Messages
165
Location
italy
So there you go... you’re a pharmacist. How long does it take for methadone to clear the body?
Is not really relevant, I did heroin many times WHILE ON METHADONE and i did get why. Why all of a sudden that changed ? I don't really think is methadone related. Could be only for the fentanyl because I tried only one time with that, but it's not logical. It's probably the same problem with heroin and fentanyl
 
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