Mixing them is fine, as stated they are the same pills just different amounts of hydrocodone in them. Just be careful and monitor how much acetominophen you take. Too much APAP leaves me with horrid stomach pains and cramps and the hydro leaves me with cottom mouth and dehydrates me and i end up with a headache unless i drink copious amounts of water with them. With the amount of pills you are taking though it shouldnt be an issue, just be careful to pay attention to your tolerance if you decide to take more than normal i wouldnt recommend bumping up your dosage drastically, but rather would say to do a gradual increase if it seems they lost their "magic". One of my first mistakes with opiates was taking too many than i should because they had lost their "magic" and i figured if 3 are good then 9 would be amazing!!!!! At that time with my tolerance i was WRONG. Ended up with horrid stomach cramps and pains, puking, headache, dizzy, shaking, the works. So if you end up a little bit more tolerant one of these times taking them, go from 2 of each or whatever to 3 of each rather than doubling it or anything. But taking the 2 different sized(?) pills together wont have any weird reactions since they are the same medicine in different amounts. So sit back and enjoy your warm blanket of happiness my man! Oh the things i would do if i could go back to having that size of tolerance again! One can dream!