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N&PD Moderators: Skorpio | thegreenhand
Microdosing Hemlock.
- Thread starter Rectify
- Start date
sekio
Bluelight Crew
- Joined
- Sep 14, 2009
- Messages
- 21,994
Coniine, you mean?
Hemlock alkaloids constitute neurotoxins and teratogens. They affect the mammalian respiration so that it is first stimulated, then depressed, becoming cyanosed, and causing respiration failure. Coniine is a nicotinic acetylcholine receptor (nAChR) antagonist. [...] Reese’s description is as follows: a headache, “imperfect vision”, pharyngeal pain, vomiting, drowsiness, gradual paralysis of extremities and death at last “from apnea”. Other symptoms may be convulsions, coma, violent delirium, salivation and involuntary discharges from the bladder and bowels. Modern major clinical effects on humans are irritation of oral mucosa, salivation, nausea, emesis, slight abdominal pain, diarrhea (uncommon), bradycardia, miosis, hypertension to tachycardia, hypotension, mydriasis, seizures following ascendant muscle paralysis and respiratory failure. Diagnosis uses blood gases, electrolytes and a plant sample. First-aid and management procedures are immediate gastric lavage or emesis following activated charcoal with a purgative drug. Treatment is mainly to ensure adequate respiratory function. The important factor is to get the patient quickly into hospital care, as the poisoning symptoms appear quite rapidly. With the help of artificial breathing such as intubation, it is possible to save the patient’s life.
Coniine is toxic to humans and 3 mg produce symptoms. Up to 150–300 mg coniine can be tolerated, which translates to 6–8 leaves (6 g)
[ref]
Hemlock alkaloids constitute neurotoxins and teratogens. They affect the mammalian respiration so that it is first stimulated, then depressed, becoming cyanosed, and causing respiration failure. Coniine is a nicotinic acetylcholine receptor (nAChR) antagonist. [...] Reese’s description is as follows: a headache, “imperfect vision”, pharyngeal pain, vomiting, drowsiness, gradual paralysis of extremities and death at last “from apnea”. Other symptoms may be convulsions, coma, violent delirium, salivation and involuntary discharges from the bladder and bowels. Modern major clinical effects on humans are irritation of oral mucosa, salivation, nausea, emesis, slight abdominal pain, diarrhea (uncommon), bradycardia, miosis, hypertension to tachycardia, hypotension, mydriasis, seizures following ascendant muscle paralysis and respiratory failure. Diagnosis uses blood gases, electrolytes and a plant sample. First-aid and management procedures are immediate gastric lavage or emesis following activated charcoal with a purgative drug. Treatment is mainly to ensure adequate respiratory function. The important factor is to get the patient quickly into hospital care, as the poisoning symptoms appear quite rapidly. With the help of artificial breathing such as intubation, it is possible to save the patient’s life.
Coniine is toxic to humans and 3 mg produce symptoms. Up to 150–300 mg coniine can be tolerated, which translates to 6–8 leaves (6 g)
[ref]
fastandbulbous
Bluelight Crew
- Joined
- Jul 29, 2004
- Messages
- 21,304
There'll be no experience reports; why? Google Socrates...
Next - microdosing monkshood?
Next - microdosing monkshood?