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Itchiness with H

Antihistamines like hydroxyzine or diphenhydramin should help, butddon't forget that antihistamines are CNS depressants and can increase respiratory depression,if you take too much.
 
^ Exactly.
Some people take antihistamines to enhance the effects but others actually enjoy this itchiness, I'm not sure why.
 
I find that a single 25mg benadryl usually suppresses the itchiness enough to make it tolerable. Doesn't go away completely, but it definitely helps. Take it like 30 minutes before the heroin. A little bit of itchiness lets me know it's about to really kick in, so I don't mind a little bit. It's when I'm itching like I rolled in a fire ant pile that it pisses me off.
 
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