Alprazom or Clonzapam but not often do I do this. The reason I say this is because when glutamate is not the correct euphoric type of feeling, it causes for me atleast not anxiety but an itchyness for something else to quell type feeling. The benzos seem to disable the glutamate release but the dopamine allows me to focus so I end up able to spend a very long time on projects/hw with the benzodiazapine taken prior. I do need about 1.5x-2x the dosage of amphetamine typically if I use this piece of benzo beforehand. (Dexedrine)
I notice if the dosage of clonzapam or alprazom exceeds .5-1 mg the required amount of amphetamine to stay stimulated quadruples.
Even 2mg of xanax seems to make 100+ dexedrine required.
And after the stimulant has kicked in if I even introduce a .25 mg xanax or .125 mg it knocks out the stimulation and I must redose amphetamine.
I had similar results for years with marijuana smoking before my daily dose of D amp where if I smoked on the amphetamine it caused anxiety but smoking a lot in advance of swallowing it potentiated the sit down and melt/focus effect however Marijuana lowers both
glutamate and gaba so anxiety had sometimes been created.
http://journal.frontiersin.org/article/10.3389/fncel.2015.00162/full
I feel that overtime with dexedrine use/abuse you can negate the maladaptivity of the brain with benzodiazpines or make addicts to amphetamine with wonky glutamate brain changes content with not endlessly raising the amphetamine dosage. Also isnt it a better ADHD Med when its softer on the brain yet your frontal cortex is activated? Thats what I feel with the piece of benzodiazpine prior like its an authentic integration into my day with less "feelable" stimulant qualities.
I have spoken to my doctor about this but he sees it as not quite a good idea which is unfortunate because I think I have more Salience/integratable motivation with the conjunction at this later stage.
I really do not see how Amphetamine and Benzodiazpines are neccessarily contradictory (upper/downer), seems like a patient
not using it for anxiety would have no tolerance/w/d or speedball like effect with a low dosage like this specifically to aid in fluidity and contentment of the adhd patient.