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Misc How long to wait after coming off sertraline (Zoloft) to use DXM

isaaccain

isaaccain

Bluelighter
Joined
Oct 1, 2016
Messages
285
Got a bottle of Robitussin and I haven't had a full dose of sertraline in about a week - 25mg 3 days ago and 50mg the day before, before that 100mg for two days and before that 50 - 75mg for about a week. I'm off it now, and just wondering how long to wait before downing this cough syrup?

Thanks
 
Sertraline half life= 66h, so 5 half life=330hours= id say about 14 days to be sure to avoid serotonin syndrome.
 
^this. 14 days is the general recommendation to wait between DXM trips (although ideally it's supposed to be a month) anyway. To be extra safe (though you should be fine), start with a lower dose of DXM than usual.
 
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