Highly abnormal reinnervation patterns 18 months after MDMA

[user666]

The paper by Fischer et al., from 1995*, discusses a highly abnormal reinnervation patterns of serotoninergic axonal sprouting were observed 18 months after MDMA administration.
Does any of you have any more information about this long-term effect of the MDMA on the brain ? e.g. has anyone studied the behavioral changes due to this "highly abnormal reinnervation" ?

* Fischer C, Hatzidimitriou G, Wlos J, Katz J, and Ricaurte G (1995)
Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (/)3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”).
J Neurosci 15:5476 –5485.

 

[G_Chem]

Well the ref has Ricaurte in the name so I’m gonna write it off instantly even if it is good research. He was quite obviously a government pawn and his little “mistake” has sullied any further research that he may put out there. It’s obvious he has bias clouding his view.

-GC

 

[nznity]

Well the ref has Ricaurte in the name so I’m gonna write it off instantly even if it is good research. He was quite obviously a government pawn and his little “mistake” has sullied any further research that he may put out there. It’s obvious he has bias clouding his view.

-GC

Magic Is fucking medicine when used properly.

 

[Rectify]

MDMA in high and repeated doses causes serotonergic 'dendritic pruning.' They grow back shorter and denser. Short term memory loss is often observed.