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Flubromazolam - Retrospective - 6 years with the Knockout Night Nurse


Staff member
Feb 8, 2006
In the mountains
Dude I can't believe you just described that phenomenon, I get something so similar from pretty much any GABAergic rebound/withdrawal, when trying to sleep. I've never been able to describe it well. It has happened from phenibut/gabapentin withdrawal, as well as GHB (really bad with GHB), and benzo rebound/withdrawal. It is like my brain becomes incredibly obsessive-compulsive and I start having a semi-dream where I am still somewhat awake but it consists of replaying a tedious and complex/abstract/strange scenario, or like I have to solve a puzzle that gets more complex the more I work at it. It is extremely annoying and somewhat alarming feeling and it makes it so hard to sleep or feel comfortable. So hard to describe, and weird, but your account is the first I've read that seems to describe something similar.


Nov 18, 2011
Pittsburgh PA via heisenberg
It was in 2014, now 6 years ago, that I acquired Flubromazolam. The moment I saw the molecule I knew I had to have it, the way the molecule is put together just SCREAMS extreme benzodiazepine. Let me break that up for you:

It has the bromine on the primary phenyl group that is associated with hard-knocking analogues as brotizolam and phenazepam. Then, further augmenting the effects, on the secondary phenyl ring there's the fluorine atom that gives rohypnol its enhanced hypnotic punch. It does not stop there because it is a -zolam drug by the added methyltriazole group.

So here you have, basically, something that is very much inbetween Brotizolam, Rohypnol, Triazolam and Midazolam in terms of structure.

I was immediately spellbound and got it from China while the first reports were still coming in. I needed no reports to see this molecule was a bell ringer through and through, you just about cannot structurally emphasize a benzodiazepine more than this one was emphasized.

This proved entirely the case.

On my analytical scale I weighed some milligrams and dissolved them in an equal number of mililiters of pharmaceutical grade propylene glycol, so 1mg/ml.

For the first test I took a then commonly established doss of 0.5ml = 500 micrograms.

What happened! In 10 min I felt it, it got way strong and within the hour a very powerful sedative effect just shoved me into bed, 2 hours early, and I slept for 11 hours, three hours more than usual, still pleasantly intoxicated for a few hour more.

I had ache that comes from having lain completely still for too long.

This was SO STRONG, I wanted nothing of this dose anymore. I had had the most restful sleep ever but this was SO restful I didnt even turn myself as I shouldve.

The next dose was 0.4ml - 400 micrograms, dosed with a syringe, squirted on the tongue (it tastes foul) and chased with some water. The effect was almost identical.

Blotters nowadays contain 250 micrograms of the stuff.

I tinkered around with the substance and settled around a dosage of approximately 100 micrograms, a standard LSD dose of an RC benzo, or roughly 75-150 micrograms, as my default dosage.

100 microgramps interrupts intense anxiety attacks, sober or drug provoked ones, and typically there's a half hour nap somewhere around 2 hours in.

This stuff, as predicted by the structure activity relationship, is as potent and hypnotic as benzos come.

In oldfashioned mental institutions, think One Flew Over The Cuckoo's Nest and earlier, the night nurse used to have a knockout drug like amylene hydrate, paraldehyde or chloral hydrate to lay out the most stubborn insomniacs. This birthed the phrase "Knockout Night Nurse".

Flubromazolam has earned the nickname "Knockout Night Nurse" with me, JYI-73 doesn't have a nice ring to it, and with "Knockout Night Nurse" you have the expectation of a swift pharmacological brick to the back of the head, which is TOTALLY what flubromazolam is about.

It is incredibly blatant as a sedative, so hypnotic that it just about feels like you took a barbiturate. This is a nonfunctional benzodiazepine, because even in the afternoon on a low dose you might take a nap and if you take a higher dose that "nap" lasts 11 hours.

I want to emphasize that there is a medical case of potentially fatal intoxication on the books of this substance at a dose of just 3mg. If you have no tolerance this hits you like a ton of bricks and benzodiazepine overdose is something that is most likely to happen with one as highly hypnotic and muscle relaxing as this one. The subjective effects are most like a barbiturate, and therefore the risks are likely higher than those of an average benzo as well.

I've used this one, on occasion, for 6 years now. I always go for the 100-150 microgram range now. I would not exceed a quarter milligram, I respect this drug to the moon and back.

With as little I need, as infrequently as I use it, its likely that Chinese gram will last me and my closest ones a lifetime.

How often do you really need to get batted in the back of the head in life? Not much - and that is really all this drug is good for: subduing raging anxiety and panic attacks and nuking the most tenacious insomias.

Cherry on the cake, it truly lasts 12-20 hours or so, so potent yet so long lived! It puts you to bed and gives a pleasant skew to the first half of the subsequent day.

You MUST liquid dose with this one. The effective dose range is the same as that of LSD and unlike LSD overdoses and drug mixes are not benign.

Proceed with caution, in the knowledge you're working with the ultimate in sedation that benzodiazepines can offer.

Tagged by Xorkoth
I have tried most of the rc bz.s. Although flublam is extremely potent, it's more like chloral hydrate. It knocks you out without any euphoria. Also, I think the only reason it has anxiolytic properties is simply because it knocks you unconscious and you can't feel anything! To me it is like a high dose of thorzine than a good bz.

But to each their own. I really can't even feel benzos anymore . Has this occured to anyone else? I think I down regulated my GABA receptors along with it's subunits. I've been on so many GABA ergics in my life that I honestly don't think they work anymore!

On top of all of that, I'm on 115mg of methadone daily for for years this time and they earn not to take any sedatives with methadone or it will SURELY cause death. . But i could hardly even fall asleep anymore, namely on prescription benzos. I take 3 mg of klonopin a day rx for over a decade..
That is the one that takes away my anxiety every time and seems sturdy (meaning it doesn't stop working immediately after a bit of nicotine like alprazolam seems to for me.
Next, I can take enormous doses of most benzos save Clonazolam. I just finished off 60 1mg Greenstone Xanax in one day and it wore off within 2 hours maybe? I was disappointed as i usual am when I am let down by supposedly strong benzos . So my cravings for GABA drugs went through the roof, causing me to call my Dr with a story about insomnia and how the one thing that ever worked for me was Temazepam! So he actually called me in 30 X 15mg Temazepam with 5 refills! So I took them all and didn't feel hardly anything! Not until the next day anyways. I felt a warm afterglow that lasted a good part of the next day but I'm thinking it was residuals mixing with my morning methadone?
The point in all of this is that taking highly potent RC GABAergics, IMO can cause you a lot of problems! One seems to be a permatolerance to gaba drugs from benzos to phenibut to apigenin to lyrica etc!
So be careful with taking potent rcs like flubrolam! You may one day develop dementia or permanent anxiety that doesn't respond to GABA ergics . Good luck! And stick to Klonopin aka Clonazepam if you want to have your anxiety diminished every time.


Jan 16, 2009
. I just finished off 60 1mg Greenstone Xanax in one day and it wore off within 2 hours maybe? I was disappointed as i usual am when I am let down by supposedly strong benzos .

I am always astounded at the level of tolerance. And it seems it does not go back down all the way after someone takes 60 alprazolam. Incredible.

But I agree with one of the earlier posts. To have the flubromazolam banner come up at the top of BL everyday should be changed or have the ability to be changed. Need to be rotated.