If you are w/d from opiates I suggest using dxm the entire time. The reason being it significantly decreases the peak w/d and w/d time. The dreaded opiate wd continue to increase in the non-dxm group, even up to a peak at day 4 when the study was ceased. The Dxm group w/d peaked around day 2 and were half as bad on the COWS (opiate w/d scale) as the non-dxm group.
http://www.hindawi.com/journals/isrn/2013/546030/
"This study shows that dextromethorphan added to clonidine regimen has a better efficacy compared to clonidine alone in controlling the mild withdrawal symptoms in male opioid addicts.
In the patients receiving clonidine alone the withdrawal symptoms increased across the study and reached their most severity after 72 hours from admission, while patients who received dextromethorphan and clonidine experienced milder symptoms. Their symptoms decreased after a peak in 48 hours from admission"
It has to do w/ the way dxm makes you forget things like tolerance and addiction that can re-wire your brain faster through NMDA- mediated facilitation.
"Conclusion: Dextromethorphan, as a NMDA antagonist, is effective in the relief of withdrawal symptoms. Hence it is very useful in increasing the efficacy of clonidine and reducing the need for opioid agonists. Added dextromethorphan to clonidine resulted in symptom reduction as soon as the second day of admission while patients experienced very few side effects."
http://www.hindawi.com/journals/isrn/2013/546030/
"This study shows that dextromethorphan added to clonidine regimen has a better efficacy compared to clonidine alone in controlling the mild withdrawal symptoms in male opioid addicts.
In the patients receiving clonidine alone the withdrawal symptoms increased across the study and reached their most severity after 72 hours from admission, while patients who received dextromethorphan and clonidine experienced milder symptoms. Their symptoms decreased after a peak in 48 hours from admission"
It has to do w/ the way dxm makes you forget things like tolerance and addiction that can re-wire your brain faster through NMDA- mediated facilitation.
"Conclusion: Dextromethorphan, as a NMDA antagonist, is effective in the relief of withdrawal symptoms. Hence it is very useful in increasing the efficacy of clonidine and reducing the need for opioid agonists. Added dextromethorphan to clonidine resulted in symptom reduction as soon as the second day of admission while patients experienced very few side effects."