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Dresden's Chemical Fluff Thread (Name-A-Molecule)

Nagelfar

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Inhaludon. (phenmetrazine ‘preludin’ + nicotine)

I was entertaining the possibility of presenting a simple molecular part, and someone else taking that as a base and adding a functional group (with heteroatoms intact, etc.), and either going back to the OP for a final addition of a branch off from that, or a third party finishing it. Would we come up with anything potentially active? Almost a form of tic-tac-toe (Were our contributions at odds with what the other intended to achieve)

Then we could each give a speculative name of the end product, rather than what we were trying to make or the concept we may have initially had but didn't reach fruition.
 

Rectify

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Ok, but first let me post one that I had just thought of before reading your post.



DAWN
1-(benzothiophene-3-yl)-2-aminopropane

Last time I did AMT I really can't say that I enjoyed it, but Dawn is probably completely different based on Nichols' finding that dimethylaminoethylbenzothiophene (DMT with a sulfur for the heterocycle) is inactive. Therefore, Dawn should act more like a pea than a tryptamine.
 

Rectify

Bluelighter
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Ok, so I'm back. I made a couple o changes to your molecule and named it...



LOVE'S
1-methyl-2-(3,4-methylenedioxy-5-azaphenyl)-3-methyl-1,4-diazacyclopentane

I'm hoping it will be lovely.

Of course, due to chirality (the molecule has 2 stereo center carbons as drawn), we are really looking at 4 molecules (2^n) here.
 

Nagelfar

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Ok, so I'm back. I made a couple o changes to your molecule and named it...



LOVE'S
1-methyl-2-(3,4-methylenedioxy-5-azaphenyl)-3-methyl-1,4-diazacyclopentane

I'm hoping it will be lovely.

Of course, due to chirality (the molecule has 2 stereo center carbons as drawn), we are really looking at 4 molecules (2^n) here.
I hadn't started yet, but I'll bite:


↑‘Jackie–Glycerin’
↓(New)

↑…when you finish start one. Basic tropane.
 

Rectify

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JOSHUA [YESHUA]
1-(4-methylthioindole-3-yl)-2-dimethylaminoethane

Happy Purim!

CH3CH2CH2OH
1-propanol
No Excise Tax!



PURE M, #96.
[HARE KRISHNA]
1-(3,4,5-trimethoxyphenyl)-2-aminoethane
Festival Of Lights!



BOOTY SHAKER
1-(3,4,5-trimethoxyphenyl)-piperazine
 
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Nagelfar

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Gaffy, did you ask me if that was an active molecule in a reported post as an accident? I doubt it would be: I was just following Rectify's previous hand-drawn version. I was going to flip where the aryl groups were, as 2,3 positions having them would likely be active, until I noticed it was the other way around. Large substitutions at the 6,7 positions lower activity, at least for cocaine-like dopamine re-uptake inhibitors.
 

Gaffy

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Gaffy, did you ask me if that was an active molecule in a reported post as an accident? I doubt it would be: I was just following Rectify's previous hand-drawn version. I was going to flip where the aryl groups were, as 2,3 positions having them would likely be active, until I noticed it was the other way around. Large substitutions at the 6,7 positions lower activity, at least for cocaine-like dopamine re-uptake inhibitors.
Fun
 

Rectify

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JOE BIDEN
1-(4-iodophenyl)-2-methylaminopropane



HARRIS
N-hydroxy-N-ethylamphetamine

H-O-H, water.
DIHYDROGEN MONOXIDE



YOCHEMOSE
1-(3,4,5-trimethoxyphenyl)-2-(hydroxyamino)ethane



NOCIOCIDE
1-(3,4-methylenedioxyphenyl)-1-carbomethoxy-3-(1-piperidinyl)-2-methylpropane



PARIS HILTON
1-(3-chlorophenyl)-2-ethylaminopropane




a FUN GUY
1-(2,3,6,7-tetrahydro-4-oxoindole-3-yl)-2-dimethylaminoethane



SESAME SAUCE
6-azabicyclo[4.3.0]nonane-3-yl 3,4-methylenedioxyphenyl ether



TRIPPER
3-(1-azabicyclo[3.3.0]octane-3-yl)-indole



EVE
1-(3,4-methylenedioxyphenyl)-2-ethylaminopropane



STAN
N-BzOMe-AMPHETAMINE
N-(2-methoxybenzyl)-1-phenyl-2-aminopropane



GLORIOUS
N-(2-methoxybenzyl)-1-(3,4-methylenedioxyphenyl)-2-aminopropane



DIETHYLAMINOASPIRIN
N,N-diethylaminocarbonyl-2-acetoxybenzene
-possible NSAID (Non Steroidal Anti Inflammatory Drug)

N-ethyl amphetamines are usually stronger than N-methylamphetamines, but the comedown is generally much worse.



PROZAC (fluoxetine)
1-phenyl-1-((4-trifluoromethylphenyl)oxy)-3-(methylamino)propane
-selective serotonin reuptake inhibitor antidepressant



STRATTERA
1-phenyl-1-((2-methylphenyl)oxy)-3-(methylamino)propane
-ADD/ADHD medicine



EDUARDO TOLUENE
methylbenzene



HALDOL (haloperidol)
4-hydroxy-4-(4-chlorophenyl)-1-(3-oxo-3-(4-fluorophenyl)propyl)piperidine
-major tranquilizer / antipsychotic (D2 antagonist)



THORAZINE (chlorpromazine)
N-(3-dimethylaminopropyl)-2-chlorophenothiazine
-major tranquilizer / antipsychotic (D2 antigonist)



3-MMC (3-methylmethcathinone)
1-(3-methylphenyl)-2-methylamino-1-oxopropane



GREEN
1-(3-methylphenyl)-2-methylaminopropane

fromd the 12 hour, 6M HCl(aq) or NaOH(aq) hydrolysis of DEET insect repellant, followed by chromatography of fractional distillation und so weiter.



DEET
diethylaminocarbonyl-3-methylbenzene



BENADRYL (diphenhydramine)
(2-dimethylaminoethyl)-(1,1-diphenylmethyl)ether
-antihistamine



DOXYLAMINE
(2-dimethylaminoethyl)-(1-phenyl-1-(2-pyridinyl)methyl)ether
-antihistamine



DIETHYL ETHER
CH3CH2-O-CH2CH3
inhalation anesthetic



KETAMINE (Special K)
2-methylamino-2-(2-chlorophenyl)cyclohexanone
-dissociative anesthetic
 
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Rectify

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DESIGNER GRAPE FLAVOR
N-acetyl-2-carbomethoxy-aniline

To be honest, I have no idea what it tastes like.



TANTALUS (resveratrol)
(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene

Entegen (E) is German for 'opposite.'
Zusammen (Z) is German for 'same.'
 
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Gaffy

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JOE BIDEN
1-(4-iodophenyl)-2-methylaminopropane



HARRIS
N-hydroxy-N-ethylamphetamine

H-O-H, water.
DIHYDROGEN MONOXIDE



YOCHEMOSE
1-(3,4,5-trimethoxyphenyl)-2-(hydroxyamino)ethane



NOCIOCIDE
1-(3,4-methylenedioxyphenyl)-1-carbomethoxy-3-(1-piperidinyl)-2-methylpropane



PARIS HILTON
1-(3-chlorophenyl)-2-ethylaminopropane




a FUN GUY
1-(2,3,6,7-tetrahydro-4-oxoindole-3-yl)-2-dimethylaminoethane



SESAME SAUCE
6-azabicyclo[4.3.0]nonane-3-yl 3,4-methylenedioxyphenyl ether



TRIPPER
3-(1-azabicyclo[3.3.0]octane-3-yl)-indole



EVE
1-(3,4-methylenedioxyphenyl)-2-ethylaminopropane



STAN
N-BzOMe-AMPHETAMINE
N-(2-methoxybenzyl)-1-phenyl-2-aminopropane



GLORIOUS
N-(2-methoxybenzyl)-1-(3,4-methylenedioxyphenyl)-2-aminopropane



DIETHYLAMINOASPIRIN
N,N-diethylaminocarbonyl-2-acetoxybenzene
-possible NSAID (Non Steroidal Anti Inflammatory Drug)

N-ethyl amphetamines are usually stronger than N-methylamphetamines, but the comedown is generally much worse.



PROZAC (fluoxetine)
1-phenyl-1-((4-trifluoromethylphenyl)oxy)-3-(methylamino)propane
-selective serotonin reuptake inhibitor antidepressant



STRATTERA
1-phenyl-1-((2-methylphenyl)oxy)-3-(methylamino)propane
-ADD/ADHD medicine



EDUARDO TOLUENE
methylbenzene



HALDOL (haloperidol)
4-hydroxy-4-(4-chlorophenyl)-1-(3-oxo-3-(4-fluorophenyl)propyl)piperidine
-major tranquilizer / antipsychotic (D2 antagonist)



THORAZINE (chlorpromazine)
N-(3-dimethylaminopropyl)-2-chlorophenothiazine
-major tranquilizer / antipsychotic (D2 antigonist)



3-MMC (3-methylmethcathinone)
1-(3-methylphenyl)-2-methylamino-1-oxopropane



GREEN
1-(3-methylphenyl)-2-methylaminopropane

fromd the 12 hour, 6M HCl(aq) or NaOH(aq) hydrolysis of DEET insect repellant, followed by chromatography of fractional distillation und so weiter.



DEET
diethylaminocarbonyl-3-methylbenzene



BENADRYL (diphenhydramine)
(2-dimethylaminoethyl)-(1,1-diphenylmethyl)ether
-antihistamine



DOXYLAMINE
(2-dimethylaminoethyl)-(1-phenyl-1-(2-pyridinyl)methyl)ether
-antihistamine



DIETHYL ETHER
CH3CH2-O-CH2CH3
inhalation anesthetic



KETAMINE (Special K)
2-methylamino-2-(2-chlorophenyl)cyclohexanone
-dissociative anesthetic
Haldol's lethalbolite is 4'Chloro8phenylpiperidine, and it's created in the liver and brain, strong D2 agonist
 

Rectify

Bluelighter
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^--I realize that. :/



GUS ANDREW TARRANT (GAT)
1-phenyl-2-ethylamino-1-oxohexane
N-ethylhexedrone (NEH)

All Work And No Play Makes Jack A Dull Boy. A Stitch In Time Saves Nine.



EMILY
1-(5-methoxyindole-3-yl)-2-dipropylaminoethane

There Can Be No Other When We Still Have Each Other!



LARRY DAVIDSON HADDEN
1-(3,4-diiodophenyl)-2-methylaminopropane
 
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Rectify

Bluelighter
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CH3CH2Cl
ethyl chloride

Na+(Cl-O-)
sodium hypochlorite



METROPOLITAN TRANSIT AUTHORITY (MTA)
1-(4-methylthiophenyl)-2-aminopropane

Handz Up, Thumbs Down Represent That Bean Town!



IZOD DOZI (Duesenberg)
1,4-dimethoxy-2,5-bis-(2-aminoethyl)benzene

A Streetcar Named Desiree

I'm in facebook jail for 3 days.



HEMLOCK INSPIRED METHYLPHENIDATE (HIM)
1-phenyl-1-ethyl-1-(2-piperidinyl)methane

The Beatings Will Continue Until Morale Improves
 
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Rectify

Bluelighter
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DON QUIXOTE DE LA MANCHA
1-(3,4-methylenedioxyphenyl)-1-ethyl-1-(2-piperidinyl)methane
 

Rectify

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Thank you!



SPACEBALLS
1,4-dimethoxy-3-(2-aminopropyl)naphthalene



Want S'more?



THE H BOMB
2,4,6-trinitrobenzene



THE F BOMB
2,4,6-trinitro-1,3,5-trifluorobenzene
 
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