Yesm tizanidine does potentiate opiate nods quite nicely.
And its orders of magnitude stronger if plugged. Too much up the arse though will knock you spark out like a bat to the head. No hangover from it, its effective, but it does seem to suppress dreaming. It blocks the very, very vivid dreams I otherwise get from nicotine sprays at high doses and I don't ever seem to remember dreams if I take tizanidine to sleep, especially rectally.
Keep the dose low that way, maybe 2mg or so should be enough. I am tolerant to it, as its a regular med for me, to suppress autistic overloading (the only downside of being spesh, to me, at least. Overloads suck, but I don't get them on tizanidine/or tizanidine can reverse one in progress far better than benzos or other GABAergics) and 4mg rectally is still enough to knock me senseless.
Try plugging 2mg though, you shouldn't be disappointed. Or micron filtering and shooting works, as does snorting, but I can't recommend banging pills. A micron filter is a must.