Bupe Do subs and Desmethyltramadol Work the Same as subs and trams?

[Hodor]

And any PDE5 inhibitor sprayed on grass clippings will be diverted Viagara, not illicit chem almost-Viagara.

Plenty of times it is, in fact, illicit-chem almost-Viagra, for example acetildenafil. Heck, nowadays it will often be an analogue of illicit-chem almost-Viagra (ex.: "hydroxyhomoacetildenafil").
https://www.tandfonline.com/doi/abs/10.1080/02652030412331272467

Chinese boner grass clipping producers have gotten to the point where they have been coming up with truly insane prodrugs of almost-viagra: Nitroso-Prodenafil is metabolized into the sildenafil analogue aildenafil and nitric oxide; an extremely unsafe combo to be sure, but certainly something that shows that these people are committed to innovation.
https://www.sciencedirect.com/science/article/abs/pii/S0731708510006631

We all know cops and customs will immediately let you go when they realize the shipment of powder and pills is not on the controlled substance list, taking your word for things.

Which is why you demand that the feds prove it is a Controlled Substance via GC/MS. Yeah, you might have to write off that shipment (you probably don't want to take the feds to court over it), but it sure as hell is less risky than straight up importing substances that are already controlled.

You don't have a person synthing cathinones already.

Are you literally implying that all that mephedrone being sold in Europe was just a conspiracy theory? And that synthetic cannabinoids are ...what, actually just mislabelled THC extracts?

The only thing that makes me think there is a single actual RC on the market anywhere in the world, is the presence of fentanyl analogues in the blood of dead people, that is not a metabolite of fentanyl, and tox screens of the occasional phenethylamine. I'll grant that in those cases some individual could reasonably create single-substitutions, but from scratch? Doesn't happen.

So, if you want to change my mind, I'd need evidence, and simply saying "this powder here is pure flubroisoquinolino-purine-pyramidine-anilopiperidino-cathino-benzo-fentanyl" won't do it.

Just a few articles (I could post many, many more):
3-FluoroPhenmetrazine (designer stim), U-47700 (designer opioid structurally unrelated to fentanyl) and Flubromazolam (designer benzo) found in the tox screening of an OD victim.
https://academic.oup.com/jat/article-abstract/41/9/765/3980194?redirectedFrom=fulltext

Analyses done by CheckIt (an Austrian drug checking/harm reduction organization): The list of designer drugs/"RC's" they detected in January of 2016 alone included 4-ChloroMethCathinone, 4-FluoroAmphetamine, 3-MethylMethCathinone, 4-FluoroMethCathinone, Pentylone, Methiopropamine, 4-EthylMethCathinone, Methoxyphenidine and 25C- & 25I-NBOMe.
https://checkit.wien/media/checkit_Warnungen_0116.pdf

Paper on the characterization of 4,4'-Dimethylaminorex sold by online vendors:
https://onlinelibrary.wiley.com/doi/abs/10.1002/dta.1668

3-MeO-PCP and 4-MeO-PCP in the urine of Swedish disso-heads:
https://www.tandfonline.com/doi/abs/10.3109/15563650.2015.1079325?journalCode=ictx20

Some of these substances, like Methiopropamine or Methoxyphenidine, were never sold as commercial pharmaceuticals, nor were any of their analogues (so they couldn't reasonably have been "diverted" from anywhere), and aren't even all that potent (approx. ~100 mg for a typical dose, i.e. nowhere near as cost-effective as a fentanyl analogue or an NBOMe, but still profitable enough to be produced for the semi-legal designer drug market, apparently).

 

[SS373dOH]

I've read that "tramadol" attaches itself to different receptors than the other opiates.. some don't even consider tramadol to be an opioid drug for that reason, so it's possible for you to feel the pain-relieving effects of tramadol while on suboxone because they will be attaching to different receptors.. I have never tried the combo myself, though. If you are wanting to start with a lower dose, try getting tramacets or Ultram?? I think is the name? Ultracet? (tramadol 37.5 mg + acetaminophen 325 mg). You could even chop them in half for a starting dose of 18.75 mg of tramadol in order to avoid risk of seizures.. then work your way up until your satisfied with the feeling.. But of course, remember not to exceed 1000 mg of acetaminophen in 1 hour and not 3000 mg within 24 hours (you could go up to 4000 mg, but I wouldn't) to protect your liver. As for the odt, I know nothing, but the others here seem to have a really good understanding of it!!​

Know thy opioids

Site	Tramadol	DSMT	Species	Ref
MOR	1,600?12,486 2,120?8,300 ≥1,000 (EC50)	5.4?18.6 17 ((+)) ≥240 (EC50)	Human Rat Human	[42][43][44] [45][46] [47][10]
DOR	>10,000 57,600?100,000	≥2,900 690 (+))	Human Rat	[42][43][48] [46][45]
KOR	>10,000 42,700?81,000	≥450 1,800 (+))	Human Rat	[42][43][48] [46][45]

Site	Ki (nM)	Action	Species	Ref
MOR	0.21?1.5 0.081	Partial agonist	Human Monkey	[20][21][22] [23]
DOR	2.9?6.1 0.82	Antagonist	Human Monkey	[20][22][24] [23]
KOR	0.62?2.5 0.44	Antagonist	Human Monkey	[20][22][24] [23]