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  • Trip Reports Moderator: Xorkoth

Diphenhydramine (1,200mg) - Experienced - Dont Take this much Ever

rangrz said:
the 5ht2a receptor is not the only receptor in your brain. Maybe some people want to try Acetylcholine and Kappa-Opioid and NMDA type hallucingins....just because you think LSD is the cats meow doesnt mean everyone else thinks it is, or that no one else wants to try anything else.

Man, is it just me, or are phsyedelic users the most elitist of the drug users.
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There will be an undertone of harm reduction in opinions expressed on this harm reduction website. Sometimes the opinions expressed about certain behaviors are extreme and sometimes sharp or rude, but I still think that most of the counter opinions here are saying "do something else, there are a thousand compounds out there and most are not as dangerous."

That only sounds elite if you don't want to here it.
 
you know, i take it back. if you dig the delerium, you dig the delerium. if anyone knows a good way to combat the drymouth, i'd prolly trip benadryl again.


also, the cannabis forum is the most elitist forum we have.
 
1,1-diphenylmethyl 2-dimethylaminoethyl ether.png


BENADRYL (diphenhydramine)
1,1-diphenylmethyl 2-dimethylaminoethyl ether
 
Whoa, a trip report zombie 🧟‍♂️!

I never understood why people abuse anticholinergics, especially benadryl and attribute it to a common misunderstanding because DPH sounds similar to DXM and there was the (imho unnecessary) recommendation to take some DPH alongside DXM to counter nausea and people got amplified hallucinations, played with the dose and guessed wrongly DPH was too a disso. But it's a delirant.

That said, they are apparently antidepressants. Scopolamine, the gold standard of delirants, was successfully trialed as a rapid acting AD. And reports like what you wrote "similar to be with a girl the first time" make me curious.

Dissociatives have a nostalgic edge to them, this has been independently confirmed by multiple individuals. I'm unsure how much of this is due to memory suppression shifting consciousness more into the moment and maybe dissos are even anticholinergics too but much less strong than DPH or scopolamine. Opioids are such ones too but they aren't nostalgic.

Once in the endless wisdom of youth I've tried 500mg DPH and it was awful. I didn't get any hallucinations but dysphoria, weird feelings and anxiety/paranoia. Thankfully the H1 antagonism put me asleep soon.

Somehow I'm still curious about the nature of these bugs and spiders, whether they are purely fictive or if multiple persons deliring at the same time would share their insects. But it's certainly nothing I'd try myself.

Still, if it's true that moderate anticholinergism was mood lifting on par with ketamine then it's be worth considering.

Would you guys mind to share more details about how DPH feels especially in relation to the described phenomenon?
 
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A decade ago I took an unlnown ammount but atleast 1200mg,not knowing it had any hallucinogenic properties, was in full opiate withdrawl n had nothing else to try n sleep after 48 hours of wding bad.long story short I was in a whole different dimension, handed my gf at the times.mother a big rubber dildo,n got picked up by the law n spent the next 72 hours in full delirium,smoking cigs n chilling with my. Gf in the jail cell, none of it actually occurring, took my brain like 2 weeks to get right.. still cant take any diphenhydramine without adverse reactions even in very small ammounts... had nooo idea wtf i was in for haha
 
@d3lnarg0 Yep, these anticholinergics have a dark side to them (and, how nice, a good part of the antipsychotics are also anticholinergics or they are combined with one to avoid dyskinesia). I've read various reports from people needing weeks to recover or who went through permanent personality changes, the similarly acting, long lived nerve agent BZ is notorious for this.

Think it's remarkable how they are somewhat oppositing to dissociatives. On the latter you are e more or less yourself but you forget most of the experience (retrograde amnesia, impaired encoding). Anticholinergics appear to mess with reality and recall but less the encoding. Both poses dangers but the choline kind sounds nightmarish.

Love to read reports though.

Long term anticholinergic use, even below delirium treshold, has been repeatedly associated with later dementia (we have had some threads in N&PD about some years back in time).

Guess this doesn't mean chline is just good as too much of it leads to depression, but maybe through over-thinking or similar effects? I certainly am an over thinker and don't tolerate the choline promoting racetams and some have nasty lasting adverse effects from overdosing on them. It appears to be a transmitter that's better left off untouched unless you react positively to moderate racetams of have dementia.

There are two kind of acetylcholine receptors though, the muscarinic and the nicotinic folks. The latter seem probably less problematic. Oh, many insect poisons and other nerve agents work by disabling cholinesterase, causing a toxic buildup of acetylcholine. So much about 'wasp spray meth' I guess.
 
ziggyjuarez said:
I would say it was about the 20th or so time I'd taken Diphenhydramine recreationally.The normal weekly trip amount was always 600mg or 24 Benadryl "Kapseals".This time was before a court date.Not haveing any money i was desperate enough to steal from a local grocery store.Not wanting to get kicked out for a small box, i decided to steal the larger 48 pack.I had no intention of swollowing the whole box of pills knowing the risks and uncomfort the higher doses bring.But when i got all the 48 pills out of the box (time consuming) I said why the hell not.In about 3 large gulps with water.All 48 pills were taken.I listened to music while i waited for the effects to come.15 Minutes later my memory gets a little hayze.from what i can remember All the classic effects I loved were there faster then normal.But a more stronger effect of nervousness was there.Normally felt when around another person when on the drug.Kinda like being with a girl for the first time.But stonger and a lot more frightning.Then pure panic hit.For no real reason just panic.I kept looking behind me, At the door and into the empty spaces of my room.Ready to let this shit hit full force i layed down on my bed looking at my blank television screen dareing for something to appear.After an unknown amount of time i was experiencing full on hallucinations in a delirious state with out realising it.I also remeber looking around my room and seeing a frightening figure looking at me.The absolute worst part of the whole trip came from a trip to the bathroom.At the time i did not realise it but i drank a gulp of "calgone take me away" body spray.I did not even know i was in the bathroom.I only know i did this because i remember haveing a terrible taste and trying to gasp for air.From here on is a total blackout.The next thing i remember is 5 hours later.I asked a relative what had happened because she was on the phone telling someone i was tweeking on crack.Apparently i left the bathroom shower on all night,Dropped a lot of music cds on the floor and was running around the house without a shirt.After five hours later the effects were still strong.Every so often i had to stop myself from grabing things that were not there, Talking to people who were not there and from tracking back and forth in my footsteps.In court i gave up on trying to comprehend and waited for pauses in there speeches, So i could say uh hu.Just understanding a simple sentence was impossable.As an overveiw i would say It's just not fun at high levels.I still enjoy Diphenhydramine at 600mg but may dare one day venture into full delirious state again.Definitely not for everyone.Be carefull:)

substancecode_benadryl
substancecode_diphenhydramine
substancecode_pharms
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8o
 
I did a whole box (can't remember whether it was 500 or 1000mg) once and it was the creepiest hallucinations ever.
Dead/zombie dog on my bedside table reaching out to me for help, old witch woman at the end of my bed, the coats on the back of my door turned into a guy strangling a woman, all while I lie there buzzing pretty much unable to move with literally the worst dry mouth ever.
Needless to say I never went over 200mg (for sleep or as a potentiator again) *shudders*
 
schizopath said:
@d3lnarg0 Yep, these anticholinergics have a dark side to them (and, how nice, a good part of the antipsychotics are also anticholinergics or they are combined with one to avoid dyskinesia). I've read various reports from people needing weeks to recover or who went through permanent personality changes, the similarly acting, long lived nerve agent BZ is notorious for this.

Think it's remarkable how they are somewhat oppositing to dissociatives. On the latter you are e more or less yourself but you forget most of the experience (retrograde amnesia, impaired encoding). Anticholinergics appear to mess with reality and recall but less the encoding. Both poses dangers but the choline kind sounds nightmarish.

Love to read reports though.

Long term anticholinergic use, even below delirium treshold, has been repeatedly associated with later dementia (we have had some threads
Click to expand...

So i actually have enough time to explain better the events.
6pm-2am. Cocaparty to help with veing 48 hours intl full opiate wd fr a 4 yr habit
3am. Liquor store is closed n i have no substances to help.me.sleep .I have a bottle of the 25mg blufootballs , fors5 i try to mash up like 15 of them in a spoon laizipy so its this chunky slop that i have no chance pf usin iv, so I swallow it with a gulp of water n grab another handfull of atleast 20+ chewem up a bit n swallow woth another gulp.of water.My ex n I ate a gew blocks from her.mothers house. Who we stay with. i eatanother handafter a few minutes of still not feeling tired, We get home and right away I for some reason think i had a rig with a nice shot of blow in it somewhere
. I am meticulously looong and geeling for it in a huge white down comforter, shortly after my ex tells me iminsane I start to see toms pf small black worms cruisimg in and out of the fabric. I dont wanna sou d even crazie so I distract my self by trying masturbate my shriveled limp cock. Being in full opiate wd i climac wothin seconds, but no ejaculation.I sit n literraly have over 40 climaxs before her Mom fpr se reason kocks on a our door, my ex is already asleep , I open the door maybe a foot and for god knows why hand her a huge rubber dick n shut the door ( we did webcam pornfor a living.why i had the toy within arms reach) She knocks again and says the police ate upstairs and they need to talk to me. I keep saying "ur fuxking wi th me right, no way " I try to pull every bit of focus tp sober up, or look it. The pigs are there to just issue me a formal complaint from a nearby gasstation that i was banned from there cause i accidentally pulled a handle off trying to open the door a few nigjts before. They ask me whats wrong with me n i tell them Im coming off benzos n opiates, I can barley pronounce anything right, They asl for ID n i day i dunno where it is.
i cany even spell my first name right when they ask.. finaly They have the info needed to verify what i said. My nerve are at ease as i sit inside waiting for them to leave after giving me the pffocoal paper banning me from the store. They come back n tell me i. Under arrest for somthong else that popped up. They cant telle.details right then. They throw me in the back of the swuad car n are talking with my Ex n her mom. Im thinkin they are asking to go into our room , which is littered with bad things, I get to the small sub station and they throw me in a holdong cell. That after a few minutes my ex enters n gives.me a cigarette n as we sit there smoking she keeps complaomgomg about how cold it is. Buy not to worry, her older sister is bonding her out, and her mom is bonding me out. At some point I walk out n go.to some decks n sign some papers n her moms there. Ignoring ms.. after a few hours Im back in the squad car and They say im being xferred to a bigger jail. I laugh n say what a waste.of time, when i. Gettomg bonded out anytime.. He asks why I think that. My response daying the girl that was there was my gf n i already had signed the papers with her.mother present, He tells me I musta done seome seriously wild stuff cause none of that had happened at all. I spend the next 36 hours n a room with newpapers lamenated to the floors and walls, I could read the articles , n when it was bed time, the night was filled with deathly screams of tortured inmates crying to.me for help. Ya fuck this substamce in high doses
. Every tool that says they see full on vivid hallucinations off a cpl gs of shrooms or hits of acid gets the secret knowledge of a legal strongest trip attainable at their local wallyworld
 
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ziggyjuarez said:
I would say it was about the 20th or so time I'd taken Diphenhydramine recreationally.The normal weekly trip amount was always 600mg or 24 Benadryl "Kapseals".This time was before a court date.Not haveing any money i was desperate enough to steal from a local grocery store.Not wanting to get kicked out for a small box, i decided to steal the larger 48 pack.I had no intention of swollowing the whole box of pills knowing the risks and uncomfort the higher doses bring.But when i got all the 48 pills out of the box (time consuming) I said why the hell not.In about 3 large gulps with water.All 48 pills were taken.I listened to music while i waited for the effects to come.15 Minutes later my memory gets a little hayze.from what i can remember All the classic effects I loved were there faster then normal.But a more stronger effect of nervousness was there.Normally felt when around another person when on the drug.Kinda like being with a girl for the first time.But stonger and a lot more frightning.Then pure panic hit.For no real reason just panic.I kept looking behind me, At the door and into the empty spaces of my room.Ready to let this shit hit full force i layed down on my bed looking at my blank television screen dareing for something to appear.After an unknown amount of time i was experiencing full on hallucinations in a delirious state with out realising it.I also remeber looking around my room and seeing a frightening figure looking at me.The absolute worst part of the whole trip came from a trip to the bathroom.At the time i did not realise it but i drank a gulp of "calgone take me away" body spray.I did not even know i was in the bathroom.I only know i did this because i remember haveing a terrible taste and trying to gasp for air.From here on is a total blackout.The next thing i remember is 5 hours later.I asked a relative what had happened because she was on the phone telling someone i was tweeking on crack.Apparently i left the bathroom shower on all night,Dropped a lot of music cds on the floor and was running around the house without a shirt.After five hours later the effects were still strong.Every so often i had to stop myself from grabing things that were not there, Talking to people who were not there and from tracking back and forth in my footsteps.In court i gave up on trying to comprehend and waited for pauses in there speeches, So i could say uh hu.Just understanding a simple sentence was impossable.As an overveiw i would say It's just not fun at high levels.I still enjoy Diphenhydramine at 600mg but may dare one day venture into full delirious state again.Definitely not for everyone.Be carefull:)

substancecode_benadryl
substancecode_diphenhydramine
substancecode_pharms
Click to expand...

I'm always super-thirsty (I literally drink up to 4 gallons of non-alcoholic fluid a day) so I think if I took that much Diph I'd shrivel up into a raisin.
I also find anti-histamines are dangerous in the way benzo's are in that you totally forget you've taken anything (with benzo's it's delusions of being sober; with AH's it's more like you just forget you're tripping) so can easily just keep taking more without realising.
Thing is, AH's also make you feel like shit. I just get SUPER-realistic hallucinations.
 
@PYTH Strange that I seem to be the only one not to get any hallucinations from 500mg. This might say something about my acetylcholine system, as choline can be pro-depressive and increase tension, both of which I got plenty by nature and the racetams, being choline promoting agents cause a strong worsening in me ...

Oh yeah, anticholinergics make you feel hot, and dry. Also it's indeed kinda stimulating but individually dependent whether that will overshadow the sedation from H1 antagonism or not, I was able to fall asleep pretty easily but had insomnia from akineton.
 
o_Oo_Oo_O

The most diphenhydramine I ever took at one time was about 300-400mg and I felt like absolute death. It was like being poisoned, possessed and going insane at the same time.

The hallucinations that I got from anticholinergic deliriants always had a very dark, evil feel to them: demonic-sounding voices, skulls popping out of my wall, etc.

Even though the logical part of my brain tells me that it was just a chemical reaction, I couldn't help but feel that it made me tap into realm that I should have left alone.

Stay Safe!!!
Dreamflyer
 
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