Hey guys, this is quite unfortunate, unwelcome, and also extremely surprising.
For several years my tolerance and response to opioids has remained constant, albeit at a very high level.
10mg IV oxymorphone provides a strong but not overwhelming rush and pleasant afterglow for several hours, occasionally 15mg is used and while it doesn't feel even close to OD territory, it's a bit more than what I'm looking for. So as I said, for over 2 years daily this has provided strong but manageable effects.....and then...
Someone decided to get acquainted with butyr fent for a mere 4 days. During this time, the usual opana doses were skipped as the BF was played with about every hour for these 4 days (BF has incredibly short duration when vaped or IV).
After this little 4 day excursions, the usual regimen was resumed...and I was astonished. I accepted that some transient increase in tolerance may result from this experimentation but Never in a million years would I have predicted THIS:
I don't like hyperbole or exaggeration so when I say that 30mg of IV oxymorphone did not produce ANY perceivable effect, I literally mean that it was as though I had shot distilled water. I actually frantically examined the syringe looking for a hole which would have allowed the 30mg to shoot out of the side and not have made it into my system. Something that absurd seemed far more likely than the alternative, that a mere 4 days of messing with BF had such a profound impact on tolerance that 30mg IV Opana (triple the amount that had provided strong, consistent effects for years) has now become imperceivable. And I cannot stress enough that this is not an exaggeration, 30mg IV opana provided ZERO response (for those that may not be familiar with opana and it's incredible potency when taken IV, it is equivalent to 600mg oxycodone or 900mg of oral morphine).
How is this possible???? Again, I had been warned that fent and it's analogs can cause fairly dramatic increases in tolerance, but come on...4 days and suddenly 30mg IV Opana had become Tylenol, when prior to this, 10mg provided a good strong experience for years.
I have since tried a 30mg IV dose 2 More times, but to no avail.
So, is this as unusual as I seem to think it is, or should I have expected that a mere 4 days of switching over to BF would produce such a profound increase in tolerance.
And more importantly, is this likely a permanent effect or is it reasonable to expect that over the next few days or weeks, assuming I resume to my typical regimen of opana, my tolerance will return to something at least resembling what it was before?
Of course I'm aware that my best bet at getting my tolerance back down is to abstain from all opioids for some time, but suffice to say that is not an option right now.
I'd love to hear anyone who has had experience w a short course of BF, and if they experienced the same shocking raise in tolerance, and if so, was this a permanent change?
Thqnks
For several years my tolerance and response to opioids has remained constant, albeit at a very high level.
10mg IV oxymorphone provides a strong but not overwhelming rush and pleasant afterglow for several hours, occasionally 15mg is used and while it doesn't feel even close to OD territory, it's a bit more than what I'm looking for. So as I said, for over 2 years daily this has provided strong but manageable effects.....and then...
Someone decided to get acquainted with butyr fent for a mere 4 days. During this time, the usual opana doses were skipped as the BF was played with about every hour for these 4 days (BF has incredibly short duration when vaped or IV).
After this little 4 day excursions, the usual regimen was resumed...and I was astonished. I accepted that some transient increase in tolerance may result from this experimentation but Never in a million years would I have predicted THIS:
I don't like hyperbole or exaggeration so when I say that 30mg of IV oxymorphone did not produce ANY perceivable effect, I literally mean that it was as though I had shot distilled water. I actually frantically examined the syringe looking for a hole which would have allowed the 30mg to shoot out of the side and not have made it into my system. Something that absurd seemed far more likely than the alternative, that a mere 4 days of messing with BF had such a profound impact on tolerance that 30mg IV Opana (triple the amount that had provided strong, consistent effects for years) has now become imperceivable. And I cannot stress enough that this is not an exaggeration, 30mg IV opana provided ZERO response (for those that may not be familiar with opana and it's incredible potency when taken IV, it is equivalent to 600mg oxycodone or 900mg of oral morphine).
How is this possible???? Again, I had been warned that fent and it's analogs can cause fairly dramatic increases in tolerance, but come on...4 days and suddenly 30mg IV Opana had become Tylenol, when prior to this, 10mg provided a good strong experience for years.
I have since tried a 30mg IV dose 2 More times, but to no avail.
So, is this as unusual as I seem to think it is, or should I have expected that a mere 4 days of switching over to BF would produce such a profound increase in tolerance.
And more importantly, is this likely a permanent effect or is it reasonable to expect that over the next few days or weeks, assuming I resume to my typical regimen of opana, my tolerance will return to something at least resembling what it was before?
Of course I'm aware that my best bet at getting my tolerance back down is to abstain from all opioids for some time, but suffice to say that is not an option right now.
I'd love to hear anyone who has had experience w a short course of BF, and if they experienced the same shocking raise in tolerance, and if so, was this a permanent change?
Thqnks
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