Opioids Could Chlorferinamine ruin Codeine?

[supersonic89]

Hey buddies,

The last week I was quite congested (it is winter where I live) and I was taking some chlorpheniramine. I know that chlorpheniramine is almost a kind of SSRI and apparently it is an inhibitor of the CY2PDA enzyme. The same that most opioids use to metabolize into more potent metabolites.

I was planning to take some Codeine today but am I afraid that this chlorpheniramine crap will inhibit the metabolization of Codeine? I'm right? Or low doses are not very worrisome (2 mg x 6 days) and I know this stuff has a long ass half-life.

 

[supersonic89]

Shit the poll is tied. Two votes for each drug. Yesterday I took 1500 mg of pregabalin (along with other substances) and with a semi-empty stomach and damn it! I get high like never before, I couldn't even speak hahaha.