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Opioids Can anyone give tips on how to sleep during opiate/opioid withdrawal?

FunctionalJnkieGrl

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Yeah, this substance class is nasty indeed (the antidepressant venlafaxine is very similar to tramadol, both structure- and mechanism wise, it is just more potent as a SNRI and doesn't metabolize to the real deal, O-DSMT, but against common knowledge it's just the metabolite, besides that venla induces headache when taking too much too fast, I feel almost no difference between these two)

I've stopped counting how many times I tried to get off venlafaxine and never made it through more than 4-5 days of this anhedonic depressive restless fatigued jittery sweaty diarrheaic hell. Morphine is a walk in the park in comparison to quit, not literally but it's much easier and I was at 600mg/d.

Baclofen seems to work for alcohol, unsure about opioids. Only tried it once and low-ish doses did nothing, above a certain threshold it became pretty uncomfortable. Sweating, bad physical feelings, weakness - not what one wants to experience when withdrawing I guess. I'd say the NMDA antagonists/dissociatives are more promising and with phenibut it's the gabapentinoidergic activity which helps not the GABA-B one but YMMV, interested in reports!

Just recently I read that dopamine agonists like pramipexole or ropinirole which are used against RLS and Parkinson's, are able to block opioid withdrawal or a good part of it (in rats, that is, but it makes sense because opioids increase dopamine and dopamine-agonist-withdrawal symptoms read like opioid withdrawal).
600mg of morphine?! Whoa! At the most, I can handle half of that (orally) and I've been taking painkillers daily for well over a decade.
 

plumbus-nine

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600mg of morphine?! Whoa! At the most, I can handle half of that (orally) and I've been taking painkillers daily for well over a decade.
Heh and I thought my dose to be more average. I know somebody who also only ever took orally (or intranasal which with morphine doesn't make a difference) and she's on 2.4 fucking gramms every second day! This substance convinced me that people aren't overblowing their dosages for whatever reason..
 

Xorkoth

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2.4 grams?? Jesus christ. I was addicted to opiates heavily for 10 years and when I relapsed after 5 years clean I took 100mg of morphine orally and it was way too much... passed out and spent the entire next day throwing up over and over again.
 

plumbus-nine

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2.4 grams?? Jesus christ. I was addicted to opiates heavily for 10 years and when I relapsed after 5 years clean I took 100mg of morphine orally and it was way too much... passed out and spent the entire next day throwing up over and over again.
Yeah I was worried when I heard about her dosage but she seems to know what she does..

How long did it take for you to build down with tolerance? Did you quit and manage 5 years straight not to touch them? Respect. I am currently dealing with like weekly relapses and tolerance just won't go down, am thinking about giving ultra low dose naltrexone a try..
 

plumbus-nine

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Yeah I did manage 5 years without a single opioid, nor any cravings. Relapsed due to experiencing an extended period of loss and pain.
I don't crave them either, much more stimulants I guess but the PAWS of morphine is so fucking bad. Sucks out all energy and converts it into dysphoric restlessness. Don't know I had high hopes for dopamine agonists but pramipexole turned out to be a sleeping pill. Then it has to be adrenergic fatigue I guess. That's hard to treat as adrenergics are anxiogenics to me. I should get ADHD drugs scripted again, the recent prolintane experiment showed me that stims can be good in withdrawal too but it's just too expensive and I can't import here, customs stop all..
 

pally pete

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Tylenol PM/Advil PM works well enough believe it or not. I threw myself into a crippling withdrawal trapped away far from home with only tylenol PM lol! Everyone thought I was a suicidal person because I was very depressed for a bit.

Opiate withdrawal really isn't so bad. It'll make you want to die but that's really all it is ;) I'd rather be dopesick beyond recognition and crapping myself than to cold turkey a ton of xanax and sieze out with absurd paranoia and rebound anxiety lol.... it really is just the first two weeks that you want to murder everyone around you. Then after those initial two weeks you can walk around and pretend to be normal while still feeling somewhat crappy.

I need to stop reliving opioid withdrawal. Just got past the worst of it again and it does not make life good at all. The pills do kind of.... but then you kind of get high and ruin your entire life. It feels nice though.
That is a spot on description. I literally couldn't have put it better myself.
 

FunctionalJnkieGrl

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That is a spot on description. I literally couldn't have put it better myself.
I hear opiate withdrawals are a cake-walk in comparison to benzo withdrawals and alcoholic DT's. Witnessing my dad endure DT's scared me out of becoming a sun-up to sundown drinker. My dad is still a heavy drinker but hopefully he kicked the meth, though I think he and my stepmom still take adderall every now and then (for productivity purposes). If I recall correctly, he only messed with meth so he could stay drunk without passing out. My biological mom on the other hand is very square--save for a drink or a small amount of weed every once in a blue moon. She's the type of person who refuses to take pills despite being in unbearable pain. My fiance is kinda like that too. I guess I take after my dad more than my mom--given I'm prone to addiction and she prefers sobriety over anything. She's a Capricorn in every sense of the sign. Nothing can get between her and her sense of self-control.
 

negrogesic

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I don't crave them either, much more stimulants I guess but the PAWS of morphine is so fucking bad. Sucks out all energy and converts it into dysphoric restlessness. Don't know I had high hopes for dopamine agonists but pramipexole turned out to be a sleeping pill. Then it has to be adrenergic fatigue I guess. That's hard to treat as adrenergics are anxiogenics to me. I should get ADHD drugs scripted again, the recent prolintane experiment showed me that stims can be good in withdrawal too but it's just too expensive and I can't import here, customs stop all..

You might try ephedrine its OTC. Not a bad pick me up and not terribly anxiogenic. Not great either but not bad. Definitely helps mild-moderate opioid withdrawal a bit from my experience, particularly in regard to the lethargy and depression.
 

pally pete

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I hear opiate withdrawals are a cake-walk in comparison to benzo withdrawals and alcoholic DT's. Witnessing my dad endure DT's scared me out of becoming a sun-up to sundown drinker. My dad is still a heavy drinker but hopefully he kicked the meth, though I think he and my stepmom still take adderall every now and then (for productivity purposes). If I recall correctly, he only messed with meth so he could stay drunk without passing out. My biological mom on the other hand is very square--save for a drink or a small amount of weed every once in a blue moon. She's the type of person who refuses to take pills despite being in unbearable pain. My fiance is kinda like that too. I guess I take after my dad more than my mom--given I'm prone to addiction and she prefers sobriety over anything. She's a Capricorn in every sense of the sign. Nothing can get between her and her sense of self-control.
Yeah, I'd take a thousand opiate withdrawals over 1 benzo withdrawal (I'm talking cold turkey withdrawals here btw...)

I may have mentioned in a previous post, when I done a 20-40 mg per day cold turkey Xanax (Alprazolam) withdrawal after a 2-3 month daily binge at that dose, which was July-September 2013. I suffered psychosis along with a whole host of other symptoms. Previous to that (2009-2013) I would just weekend binge on a few hundred milligrams of Xanax or equivalent doses of another benzo.. usually Diazepam or Temazepam. So I'd had my far share of traumatic benzo withdrawal related incidences prior to this.

But the September 2013 incident was by far and away the worst experience of my Iife.

I became catatonic.
 

negrogesic

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Doesn't seem to agree with you here - brief.fm (psychiatryonline.org)

Yeah to be frank that "brief report" is sort of meaningless and doesn't say much about ephedrine, keeping in mind the description of their "Method":

Method

We reviewed all 1,820 FDA MedWatch reports of adverse events concerning herbal ephedra as of Sept. 30, 2001

You can do the same thing for a summary or adderall MedWatch reports and it will paint the same picture. In the end its an ok OTC stimulant of relatively safety low doses. Thats why its sold OTC. And keep in mind I'm not referring to sketchy herbal ephedrine but a pharmaceutical preparation sold as "bronkaid". However the real issue with ephedrine is not some unusual tendency to induce psychosis but the cardiovascular issues.
 

axe battler

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Pregabalin is by far my favourite opiate withdrawal killa! Depending on how many nights of insomnia you've had then sometimes just forgetting about it can help your sanity wonders instead of lying sweating and spinning in circles
 

pally pete

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Yeah to be frank that "brief report" is sort of meaningless and doesn't say much about ephedrine, keeping in mind the description of their "Method":

Method

We reviewed all 1,820 FDA MedWatch reports of adverse events concerning herbal ephedra as of Sept. 30, 2001

You can do the same thing for a summary or adderall MedWatch reports and it will paint the same picture. In the end its an ok OTC stimulant of relatively safety low doses. Thats why its sold OTC. And keep in mind I'm not referring to sketchy herbal ephedrine but a pharmaceutical preparation sold as "bronkaid". However the real issue with ephedrine is not some unusual tendency to induce psychosis but the cardiovascular issues.
I should know better than to trust anything to do with MedWatch/FDA.
 

negrogesic

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I should know better than to trust anything to do with MedWatch/FDA.

Well its not so much that, the issue is that its simply a summary of adverse reactions associated with "herbal ephedra", which was banned years ago.

Ephedrine can cause severe cardiovascular adverse reactions, that is the bigger concern. It generally happens in the predisposed and in concert with heavy exercise.
 

Xorkoth

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Pregabalin is by far my favourite opiate withdrawal killa! Depending on how many nights of insomnia you've had then sometimes just forgetting about it can help your sanity wonders instead of lying sweating and spinning in circles

Yeah it is, I'm 2 days off from any opioid (had 0.8mg of suboxone 2 days ago, a few doses every 2 days before that, no kratom for like 8 days I think) and been taking Lyrica the past 2 days. I feel absolutely fine, good really. yesterday was wild, I was high as hell and loving it. Tolerance builds very fast though. Gonna wake up tomorrow and see where I'm at, but I also have gabapentin to alternate.
 

pally pete

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Yeah it is, I'm 2 days off from any opioid (had 0.8mg of suboxone 2 days ago, a few doses every 2 days before that, no kratom for like 8 days I think) and been taking Lyrica the past 2 days. I feel absolutely fine, good really. yesterday was wild, I was high as hell and loving it. Tolerance builds very fast though. Gonna wake up tomorrow and see where I'm at, but I also have gabapentin to alternate.
Keep up the good work.

Although, I find dosing on Pregabalin for so long, and then using Gabapentin - I find the Gabapentin to be slightly redundant.
 
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