I take ZzzQuil nightly (which is basically just diphenhydramine with alcohol) and it does help with restlessness to some extent.Loperamide to stop the shits and pregabalin (best aid, w/o tolerance to it it's pretty much like a narcotic), centrally acting antihistamines like OTC diphenhydramimne/doxylamine, or mirtazapine (strongest antihistamine available) ... clonidine, possibly a SSRI aid with the restlessness. If you respond to it and don't have tolerance too, OTC DXM can be a very good aid too.
I take Melatonin and ZzzQuil nightly on top of my pain meds. I never cared for xanax, valium, ambien, or seroquel though. They make me feel drained in the worst way.Depends on the severity of the withdrawal. For me, a few times sleep was not an option, and when I stopped buprenorphine a year and a half ago I haven't slept more than 2 hours a day, in 3 weeks, no matter what I took. I used pregabalin (Lyrica) + clonazepam (Klonopin) + diazepam (Valium) + midazolam (Versed/Dormicum) + zolpidem (Ambien) +mirtazapine (Remeron) + melotonin +..."all other natural sleep aids". I have big tolerance to benzos though. The only thing I haven't tried is quetiapine (Seroquel) and clonidine. Sometimes sleep is really not an option. For less severe withdrawal pregabalin should suffice. From there on you add on what you are most comfortable with (near full list disclosed in this post and post above already). Hope it doesn't get that rough though.
-echo (formerly PL)
Morphine and oxy are pretty much the only pain meds I mess with these days. I absolutely hate seroquel and DXM though.For higher doses tapering is easier imho and becomes more and more difficult the more you get close to zero. Also I'd really really invest into some emergency stock which you buy and put somewhere deep into the cabinet only to touch when you're running out. Taper down with that as much as possible - it can save you big amount of suffering. Also really really get a script for pregabalin - if you can get only one med, get that! Dunno, the docs say clonidine, don't know whether for serious dependencies that one is to prefer but imho pregabalin is a different level, without tolerance you won't need the supratherapeutic dosages sometimes mentioned but tolerance builds incredibly fast so don't use until necessary.
Seroquel is shit. The only usable dosages are like max. 50mg and below, better 25mg and below. With any higher you'll get relevant amounts of a metabolite which acts as a norepinephrine reuptake inhibitor and this increases withdrawal intensity. Also the dopamine antagonistic properties will add to the shitty feelings of which a good amount comes from the sudden drop in dopaminergic activity, you want more of that not less.
If you happen to have an open minded doc, or to live in a part of the world where access to medicine is more liberal, get memantine. Really. Research it beforehand, it's a strong tool when used above the indicated dosages, but also exceptionally safe for the body (people tolerate 200mg and upwards - depending on your individual constitution, this much can and will put you into a coma for several days, but it won't kill you). For me like 60mg could mask the withdrawal from 120mg morphine XR completely and after the second administeration tolerance was low enough for regretting to take 15mg. It's got its rough edges but it works. Pregab + memantine (+ loperamide and other comfort meds if needed) make the best currently available withdrawal aid imho. The memantine is initially stimulating (not the cold restless variant but usable energy) but at day 2 or 3 you'll sleep.
Dextromethorphan might work similarly when tolerated.
I can vouch for diphenhydramine causing RLS in higher doses, but taking the recommended dose has served me well so far.Stay away from benadryl and antihistamines during withdrawal as mentioned by a mod in another thread it will trigger horrible rls and anxiety. This actually caused me to ruin a withdrawal and relapse one time because I took a benadryl and it was crazy RLS and anxiety.
That's my fiance's suggestion for anything. Haha. It helps, but I can't stay in there forever and then its back dealing with discomfort once I step out of the shower.