ADHD, Antidepressant, Sexual Side Effects...

[And12]

Hey everyone. I have been taking the following since May 2014


30mg Cymbalta (duloxetine) at night for anxiety
2.5mg - 5mg doses of Dexamphetamine/Dexamfetamine/Dexedrine IR up to 3 times a day.
2.5mg melatonin at night


So here we are in 2016 and its coming up to the two year mark that I started this combo. This combo has made me a very functional person and improved my mental well-being quite considerably.


The norepinephrine effects from Cymbalta have helped considerably... I have a real 'get-up-and-go' attitude and lots of motivation to do things and excellent mental organisation and planning. The cymbalta also helps my anxiety which in turn allows me to take dexedrine IR for my ADHD to effect dopamine to allow me to focus without feeling any intense anxiety.


I have always had sexual side effects from the Cymbalta but these only bothered me occasionally as I enjoyed all of the beneficial effects from the combination due to the positive impact that they have on my life.

Another related issue that I am experiencing with the Cymbalta is that I am finding myself with no desire for romance or desire to romantically connect with women... it is like romance and the feeling of love has been switched off in me. I was not like this before I took Cymbalta.


However, just recently these issues are indeed starting to bother me more and more... I cannot feel any interest to connect romantically with women like I used to prior to ever taking Cymbalta... I have no libido whatsoever (before Cymbalta my libido was through the roof!!) I have no lust, desire, fantasy.... nothing. I know this is not normal and I want to get these things back.
When I see a nice woman... I think 'she is nice' 'dayyumm' but then frustration that I have no libido to pursue what I desire.


On top of these things, I find it difficult to obtain an erection (I would note that this is not always an issue). I feel very 'de-sensitized' down there... for example..when I am receiving a blow job it is like there is nothing happening and I get so so bored, annoyed and embarrassment.... when I climax it is very short and then crash back down losing the s***ty erection that I managed to obtain and quickly find myself completely unable to recover and I don't have the desire to recover in order to 'get going again' either.


I really do not know what to do about all this Does anyone have any ideas?

Disclaimer: Dexedrine is the only ADHD medicine that I can take as the others including Methylphenidate and Strattera due to the side effects they gave me. Dexedrine IR is the best out of a bad bunch for me.

 

[bobby1978]

Doesn't Duloxetine also inhibit serotonin reuptake? Because that can certainly hurt your libido, especially over time. Oddly, I would think the dexedrine would overpower it and make you more horny, but that's just my initial impression, and obviously i'm wrong in this case.

I used to take panax ginseng when I was on paroxetine (an ssri, not an snri, but still) and found that it helped a lot in the libido department. Not to mention weed. Those two together make me feel like I'm about 18 sexually (I'm actually 37).

I'm not advocating you just throw that stuff into the mix, important to be careful of course and think about what you're combining, but just sharing a couple ingredients that have helped me a lot in that regard.

 

[And12]

Doesn't Duloxetine also inhibit serotonin reuptake? Because that can certainly hurt your libido, especially over time. Oddly, I would think the dexedrine would overpower it and make you more horny, but that's just my initial impression, and obviously i'm wrong in this case.

I used to take panax ginseng when I was on paroxetine (an ssri, not an snri, but still) and found that it helped a lot in the libido department. Not to mention weed. Those two together make me feel like I'm about 18 sexually (I'm actually 37).

I'm not advocating you just throw that stuff into the mix, important to be careful of course and think about what you're combining, but just sharing a couple ingredients that have helped me a lot in that regard.

Yes duloxetine is an SSNRI Selective Seratonin and Norepinephrine Reuptake Inhibitor.

I find the dexamphetamine does seem to increase somthing sexually. I am not sure what it is as I cannot quite put my finger on it but I think it raises my sexual tension perhaps.

I am very thankful that you have shared this with me regarding the panax ginseng as an idea for me to pursue so I can attempt to increase libido, interest and hopefully sensitivity too.

When you refer to panax ginseng do you mean Korean Ginseng or another ginseng? Which ginseng should I be looking into? I will need to determine one to try and then research it's co-interactions with dex and duloxetine.

 

[And12]

Bump ( See above )

 

[m314]

Dexedrine increased my sexual desire at first. After a few years it ended up killing my sex drive. It also made it difficult to stay hard. Viagra helped, but having to carry viagra around and try to time it right when I thought I might have a chance of getting laid, it got old. Even with viagra, I felt desensitized on dexedrine. Climaxing was impossible sometimes.

I don't know anything about cymbalta. I know I feel better personally having quit dexedrine. My sex drive is back. I'm actually motivated to date again and find a new girlfriend.

 

[And12]

What is the PANAX Ginseng what type is that?

 

[And12]

Dexedrine increased my sexual desire at first. After a few years it ended up killing my sex drive. It also made it difficult to stay hard. Viagra helped, but having to carry viagra around and try to time it right when I thought I might have a chance of getting laid, it got old. Even with viagra, I felt desensitized on dexedrine. Climaxing was impossible sometimes.

I don't know anything about cymbalta. I know I feel better personally having quit dexedrine. My sex drive is back. I'm actually motivated to date again and find a new girlfriend.

What dosage of dexedrine where you on?