So ketone supplementation has been a thing for a while now, and touted by some as aiding in fatloss and enhancing performance.
This study may make you reconsider:
https://www.ncbi.nlm.nih.gov/pubmed/28750585
Ah - but they burned more fat you say. Well, as Anthony Roberts points out in his blog (worth a look):
In other words, if you're happy to spend time exercising less efficiently, then exogenous ketones may have some utility purely for fatloss (reduction in performance aside). But for most, that's just not a realistic or desirable trade-off.
This study may make you reconsider:
Nutritional ketone salts increase fat oxidation but impair high-intensity exercise performance in healthy adult males.
2017 Oct
Abstract
This study investigated the impact of raising plasma beta-hydroxybutyrate (β-OHB) through ingestion of ketone salts on substrate oxidation and performance during cycling exercise. Ten healthy adult males (age, 23 ? 3 years; body mass index, 25 ? 3 kg/m2, peak oxygen uptake, 45 ? 10 mL/(kg?min)-1) were recruited to complete 2 experimental trials. Before enrollment in the experimental conditions, baseline anthropometrics and cardiorespiratory fitness (peak oxygen uptake) were assessed and familiarization to the study protocol was provided. On experimental days, participants reported to the laboratory in the fasted state and consumed either 0.3 g/kg β-OHB ketone salts or a flavour-matched placebo at 30 min prior to engaging in cycling exercise. Subjects completed steady-state exercise at 30%, 60%, and 90% ventilatory threshold (VT) followed by a 150-kJ cycling time-trial. Respiratory exchange ratio (RER) and total substrate oxidation were derived from indirect calorimetry. Plasma glucose, lactate, and ketones were measured at baseline, 30 min post-supplement, post-steady-state exercise, and immediately following the time-trial. Plasma β-OHB was elevated from baseline and throughout the entire protocol in the ketone condition (p < 0.05). RER was lower at 30% and 60% VT in the ketone compared with control condition. Total fat oxidation was greater in the ketone versus control (p = 0.05). Average time-trial power output was ∼7% lower (-16 W, p = 0.029) in the ketone condition. Ingestion of ketone salts prior to exercise increases fat oxidation during steady-state exercise but impairs high-intensity exercise performance.
https://www.ncbi.nlm.nih.gov/pubmed/28750585
Ah - but they burned more fat you say. Well, as Anthony Roberts points out in his blog (worth a look):
Total fat oxidation was greater with ketone use , but here's where things get a bit confusing if you're someone who does timed cardio (i.e. half an hour on the treadmill or stairmaster). This study used total calories burned as the end point of the time trial, meaning both the ketone and placebo group burned the same amount of calories (but it took the ketone group longer).
You're burning a higher percentage of your energy from fat with ketone use, but you're also using less energy. So you're burning a higher percentage of a lower number - which intuitively isn't the best tradeoff.
In other words, if you're happy to spend time exercising less efficiently, then exogenous ketones may have some utility purely for fatloss (reduction in performance aside). But for most, that's just not a realistic or desirable trade-off.