Three New SARMS on the Horizon

CFC

CFC

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Those of you that take an interest in SARMS will know there's always a tons of hype surrounding potential new compounds coming onto the market. Most of the time, they turn out to not deliver what was promised.

However these three may deserve some attention when (or if) they finally arrive on the mainstream research chemical scene: LG121071, ACP-105 and LGD-3303.

Ergo-log's written a nice little summary over at their website for those interested.
 
Interesting on the last one LGD-3303...what does it mean by 'replace testosterone production' though??
 
I just means 11mg/day is roughly a TRT level equivalent (compared to natural testosterone at around 4-7mg/day). It's not quite as weak as it seems though, since it has to survive digestion; of the bioavailable component it's a pretty active compound.
 
So these SARMs act on AR in a similar way as Testosterone? Or is it that it has similar strength in effects at that dosage level, despite not being the same effects?

If the latter, does this also allow for things such as Trenbolone to be compared to "TRT dosage" even though it certainly doesn't exhibit the same effects as testosterone at equiv dosage?
 
They don't actually know exactly how AAS or even SARMs work in terms of how they promote protein synthesis, since they know there are other mechanisms at play besides the AR. They're still trying to resolve how many mechanisms there are, how they work, and what different compounds target them.

In terms of this study, the comparison is based on how much muscle was gained, eschewing any need for a detailed explanation. So yes, you could compare castrated+TREN to non-castrated, which is usually how they calculate the effectiveness of AAS in all studies. However, before you ask, I don't know how may mg of tren would equate to a natural non-castrated male without doing some reading lol =D
 
^^first part of your post makes me think of anadrol. Very weak binding affinity but potent steroid.
 
I've been off the scene a while have they actually found any sarms that are
1. Worthwhile
2. Don't cause yellow vision or partial blindness
3. Don't cause shutdown of hpta
 
In short no, lol. But if you're willing to pretend you can take SARMs and still be 'natural', then it probably beats some pro-hormones.
 
Hey guys a bit late as iv'e only just joined but thought i'd mention that iv'e done gw-50156 for a cut at 20mg a day for 8 weeks. This stuff does work, I was in a caloric deficit but even so this stuff definitely got me to my most shredded point (went from about 10% to 6-7%). My cardio however didn't really increase, although I was quite cardiovascular fit before i started the cycle. The best thing was no side effects whatsoever. I know this wasn't one of the 3 that were mentioned however thought you guys might be interested. Cheers.
 
Look into Yk-11 its the MOTHER of all sarms. I dont knwo if this breaks the rules [mod-edit: cfc]
 
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No, completely different category. Most vendors will group AI's, SERMs, and SARMs under the same category of research liquids. I never ventured into that territory of SARM's... I have to do more homework to have a clear input.
 
On that note, ostarine is considered a SARM; any feedback on usage? I've read into it, but didn't know if the bang would be worth the buck. It's one thing to read past data, but more current input is always appreciated.
 
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