I thought it was well known that the several other psychoactive compounds in shrooms, while lower in dose than psilocin, have very profound effects on the nature of the experience. Such that different strains of shrooms, even if adjusted to give precisely the same mgs of psilocin are very well known to cause extremely different set of effects. Look up psilocybe cubensis on wikipedia or elsewhere and you can read alot about the other compounds and the reports by many users that they have a large impact on the trip.
Much more complex than either pure 4-aco-dmt or pure 4-ho-dmt. And always ALOT more challenging, physically, mentally and emotionally. One may on occasion prefer the deeper challenge, and on other occasions prefer the "easier", purer experience of the simple chems. They are different, is all, each with its own uses.
It is definitely well-known that mushrooms contain a variety of other tryptamines as well, and that different species/strains tend to have different ratios. But many people believe that the effects are just due to psilocin because the others (baeocystin, sometimes some DMT I believe, and others) are inactive (which they basically are taken alone), or in the case of psilocybin (4-PO-DMT) they are just converted in vivo to psilocin, and they thusly believe that perceived differences between strains of mushrooms are placebo, and that the only real effect is from psilocin.
Personally I find this to be kind of a silly idea. For one thing, several users on this forum a couple of years back obtained pure baeocystin and found it to definitely have subtle effects, mostly body-related (energy, limb movements, etc). And anyway, if we are to accept that some drugs can synergize with others, as in the case of LSD and MDMA, to create new effects that are not seen with either alone, then why couldn't the inactive or barely active tryptamines synergize with the psilocin to create new and different effects? And who knows if there are compounds in the mushrooms that, when ingested, occupy certain receptor sites or perform other neurochemical-level functions that allow the psilocin to work in different ways? Mushrooms and other plant-based psychedelics, and any plants or really any life-form for that matter, are complex organic chemical soups. There are all kinds of extremely complex reactions and activity and chain-reactions going on all the time. It seems a lot more likely to me that introducing new tryptamine alkaloids, and a fair variety of them at that, would alter the effects of psilocin. I would like to hear a convincing argument otherwise.
This is separate from the question of whether 4-PO-DMT/psilocybin, and by extension 4-AcO-DMT, is just a simple prodrug of psilocin, or if it's like I suspect, that everyone has unique levels of enzymes that make it so that for some it is quickly converted to 4-HO-DMT and basically is qualitatively identical or nearly so to psilocin, and for others it is converted more slowly and various amounts of unconverted psilocybin/4-AcO-DMT pass through the BBB and are experienced directly.
And I totally agree that the pure compounds are much "easier" experiences, although I've had a very intense ego-crushing and terrifying trip on pure 4-HO-DMT. Mushrooms are much more complex and I prefer them, but also am the most cautious of them.
My experience is very similar.
4 aco dmt comes on in 15-30 min and the main effects are done btwn 2-3 hours.
But i do get a residual stimulation that wont let me sleep till hour 5 or 6.
Its a nice couple of hours though where i reflect on the experience.
As far as being similar to dmt or mushrooms.
I find low doses to be like a DMT afterglow and high doses are similar to mushrooms but without such anxiety.
It's weird... for me, 4-AcO-DMT is pretty sedating. I've actually passed out on very strong experiences and gotten very drowsy during low-dose experiences. DMT doesn't have this effect but it is still relaxing. However, psilocin and mushrooms make me pretty stimulated (except for a few mushrooms I've had) and very wanting to move around.
