Hypothetically speaking, how long would someone have to wait to start taking their prozac again after 3 month meth relapse?
Kratom: There is this presumption Kratom is safe, it's not. Granted, it's harder to OD on it than regular opioids, but you can still OD on it. SPECIALLY if you combine it with well, anything. There's not enough data. There have been cases of deaths purely due to Kratom, but the majority involve others drugs. One case was propylhexedrine, others drugs that have been involved in Kratom deaths include alcohol, venlafaxine, mirtazapine, diphenidramine, zoplicone, citalopram, lamotrigine, etc. We know very little about this drug, it has a structure that's very versatile and it's shared by yohimbe, ibogaine, reserpine, basically all pharmacological groups, and it's likely there's more to it than a simple opioid agonist.Mitragynine is metabolized in humans via phase I and phase II mechanisms with the resulting metabolites excreted in urine. In in vitro experiments, kratom extracts inhibited CYP3A4, CYP2D6, and CYP1A2, which may help explain the combined drug toxicity. Basically, if you take kratom, take it with respect and avoid mixing it with pharmaceuticals, or at least check first.
Maybe not deadly but how kpins and weed combo?
I would bet there's plenty of sedation but nothing life threatening, like Hypoxia when opioids are thrown into the mix with clonazepam. Cannabis is more about acetylcholine inhibition. Though some of the real Heavy indica edibles might have you in a 14 hour zombie like state if mixed with copious amounts of clonazepam.