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Harm Reduction ⫸DANGEROUS Drug Combos⫷

CoastTwoCoast

Bluelighter
Joined
Feb 18, 2016
Messages
5,837
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Dancing on the corpses' ashes
Summary: Lyrica can alter judgement and mask the effects of stimulants, creating a potentially deadly load on the heart, and the brain and body.


I feel my combination of lyrica and insulfated focalin is downright terrible. I take vyvanse in the morning, a dexedrine later, feel spun and irratable, drink lots of lyrica and feel it go away and feel drunk. Then when I get off work I start sniffing 10mg focalins. One focalin sober will make me spun. But on lyrica I'm sniffing them like it was cocaine. Over the period of several evening hours railing about 8 10mg focalin, If I did that sober I'd feel like I was having a heart attack. This combination must be very hard on your mind and body.

I was hallucinating my field of vision would flash white every few seconds.
I can see how that happens. I remember being caught up in a Gabapentin/Vyvanse combo that went bad, led to paranoia.
Then Gabapentin/Ritalin.

I think Gabapentin/Lyrica potentiates amphetamines so it’s something to look out for. Or like you said, it can mask the stim effects more.

It’s exhausting actually. Glad I’m not on any amphetamines anymore. Still kinda miss it though because there’s no motivation now.
No one’s heart could put up with that kind of abuse for long and you’re constantly dehydrated.
 
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Legally High

Bluelighter
Joined
Sep 21, 2014
Messages
224
Right, I no longer take amphetemines as they have no purpose for me and just lead me to use downers. Creates a nightmarish vicious cycle.
 

peaceheeb

Greenlighter
Joined
Sep 19, 2017
Messages
20
Much needed sticky. Cocaine should definitely be added under alcohol though.

"Some studies suggest that it may be more cardiotoxic than cocaine and "it also carries an 18- to 25-fold increase over cocaine alone in risk of immediate death".

https://en.m.wikipedia.org/wiki/Cocaethylene
Cocaethylene is an interesting one for. I've never seen definitive proof of it being so much more cardiotoxic, though.
 

ConstantDenial

Greenlighter
Joined
Oct 20, 2017
Messages
3
Hi.
I am new to the forum but like many others have been lurking via google searches for months. I've been an opiate/oid addict for over ten years with brief stints of clean time. I am currently addicted to codeine, commonly considered an easy one to quit. However with 'stronger' opioid dependence in my past, this one is the one that I'm stuck on! I've read about many withdrawal aids and I have got my hands on all Thomas recipe ingredients except benzodiazepines which I refuse to touch, and boxes of loperamide. I also have doctor prescribed amitriptyline for sleep and would like to introduce DXM in small regular doses through the first 4-5 days. I also have my last 200 codeine phosphate 30mg tabs of which I take 1000 mg per day in two 500 mg doses, and want to rapid taper by dropping by one quater of the doses per day as I introduce the 'withdrawal aids'.

My question, if anyone can help, is does anyone know if there are any complications using these things together?! On paper it seems like a great plan, but I need the help of better minds here.
Huge hello to all and big respect to Bluelight, genuinely reducing harm with us lot.
 

Jabberwocky

Frumious Bandersnatch
Joined
Nov 3, 1999
Messages
44,995
Location
Looking-Glass Land
Depends on the specific antidepressant, but generally not at all a good idea. If you’re being prescibed an antidepressant and it isn’t working for you after giving it a month or two (assuming there aren’t shitty side effects), try something else.
 

Jabberwocky

Frumious Bandersnatch
Joined
Nov 3, 1999
Messages
44,995
Location
Looking-Glass Land
Hi.
I am new to the forum but like many others have been lurking via google searches for months. I've been an opiate/oid addict for over ten years with brief stints of clean time. I am currently addicted to codeine, commonly considered an easy one to quit. However with 'stronger' opioid dependence in my past, this one is the one that I'm stuck on! I've read about many withdrawal aids and I have got my hands on all Thomas recipe ingredients except benzodiazepines which I refuse to touch, and boxes of loperamide. I also have doctor prescribed amitriptyline for sleep and would like to introduce DXM in small regular doses through the first 4-5 days. I also have my last 200 codeine phosphate 30mg tabs of which I take 1000 mg per day in two 500 mg doses, and want to rapid taper by dropping by one quater of the doses per day as I introduce the 'withdrawal aids'.

My question, if anyone can help, is does anyone know if there are any complications using these things together?! On paper it seems like a great plan, but I need the help of better minds here.
Huge hello to all and big respect to Bluelight, genuinely reducing harm with us lot.
The amitriptyline may cause constipation when used concurrently with codeine. It also may potentiate you codeine, so it might be helpful to taper.

Codeine might be considered a weaker opioid than heroin or morphine, but, especially at a gram/day, it isn’t any easier to get off. Try ORT if you want off. Or lots and lots of comfort meds.

When you try the amitriptyline keep the dose low, like 10mg to start. Adjust from their. It can have some shitty side effects, but it isn’t super problematic unless you start taking high doses.

What do you take the codeine for (assuming you’re getting it from a doctor)?
 

Scrofula

Bluelight Crew
Joined
Apr 27, 2017
Messages
5,420
Location
California
What do you think about meth and antidepressants?
"Antidepressants" is way too broad. But I can tell you from experience that there's no major interaction between meth and SSRIs (Zoloft, Prozac, Effexor, Lexapro . . . ). There's no risk of serotonin syndrome.

Meth can interfere with other antidepressants like bupropion/Welbutrin or clonidine (probably not dangerously), and probably a lot of tricyclics.

Obviously, it's very dangerous to take with MAOI's, just like it's dangerous to take anything with MAOI's.

There's a risk if you're taking an "atypical antipsychotic" to help with depression, like aripiprazole/Abilify or quetiapine/Seroquel, of a thing called neuroleptic malignant syndrome I think, that I don't know much about but sure doesn't sound good.

But that's just chemical interactions--if you're in treatment for mental health, street drugs aren't usually a helpful adjunct.
 

benzoheadplus44

Bluelighter
Joined
Feb 15, 2008
Messages
315
Dangerous... Dxm + bupropion (wellbutrin) if dxm is taken at recreational levels while on bupropion it can become very dangerous
 

Jabberwocky

Frumious Bandersnatch
Joined
Nov 3, 1999
Messages
44,995
Location
Looking-Glass Land
Agreed. Somehow I never had that issue, but other well may, especially if taken together and high dose of buproprion is being used. I’m not suggesting this is at all safe, but I had no issues taking 150mg Wellbutrin and high doses of DXM (again, not safe - I was rather desperate for anything that would help getting off methadone at that point, and NMDA antagonists can be very helpful with that).

I didn’t notice the above post I quoted also referred to taking buproprion, but it’s good to note regardless.
 

Abhas

Greenlighter
Joined
Dec 24, 2017
Messages
1
Nice info

Can you please explain more about ativan+weed please
 

Scrofula

Bluelight Crew
Joined
Apr 27, 2017
Messages
5,420
Location
California
Howdy, Abhas.

You're in the "Dangerous Combination" thread. I'm pretty sure there's no serious risk combining weed with lorazepam/Ativan, if that's what you were wondering. Mentally, it might even help. There is the risk of a sudden desire for a nap, maybe, and it would only make you more impaired w/r/t operating heavy machinery.

Right now I kind of like the idea of getting stoned, plus a couple Ativan, and driving an excavator around, kind of aimlessly digging trenches till I got stuck in one.

Then I'd look up and realize . . . I was stuck in a trench the whole time.



And that's why you don't mix the two.
 

cyberius

Bluelight Crew
Joined
Mar 11, 2013
Messages
1,575
Warning to wellbutrin XR users

Do not take psychedelics while using wellbutrin.

Cannabis
Mushrooms
LSD
Ketamine
Misc designer psychedelics and dissociatives

All have grossly augmented effects leading to a very unpleasant experience (best case scenario). WB and Ketamine in particular nearly killed me and using the above suvstances in low doses led to a very unpleasant and dirty experience
 

Razorian

Greenlighter
Joined
Dec 27, 2017
Messages
1
I have been doing street drugs for about 4 years maybe 5 now and was getting prescribed 8mg hydromorphone before i did any street drugs for about 4 years prior to my doctor retiring and leaving me with nothing to ween me off but my dad had already been going to methadone clinic for i dont know exactly how long but its way up there about 10+ years and was going once a month and getting prescribed 120 a day and he only needed 40 a day so if it wasn't for him i'd of been in a very bad situation but 1 year and 3 months ago he quit cold turkey and with all these new laws on pain meds its very hard to get prescribed legally anyway sorry for the small rant but just wanted to give you a little background. also i've never shot up anything except in the hospital where they give me the pain medicine through IV but I'm not stupid i've NEVER mixed drugs that obviously should not be mixed such as heroin and oxymorphone or something like that. The only drugs i've done at least once is crack, cocaine, theres to main pain pills to list i've tried so ill just say i've tried the strongest except for fentyl or however you spell it the strongest ive tried is either 8mh Hydromorphone or 40mg oxymorphone idk which is stronger but i think oxy is, ive tried meth once it was ok and for me didnt leave me up for days like people say it does just made me really happy basically, i've tried heroin about 10 to 15x and ive only tried it from 2 different people one guys stuff was garbage which i didnt know at the time because i hadnt tried it before, the second guys stuff was waaaay better i'd already been taking 1-2 40mg oxymorphones a day and was out of state so couldnt get anything but H anyway 1 point of his would leave me feeling gooooood, 2 points made it very hard to stay awake (BTW i snorted it every time) and actually only did 2 points of his once because it was too much for me, lets see i've done marijuana i dont do it much anymore maybe once a week sometimes once a month sometimes i dont want to for 3-4 months but i've tried tons of different kinds (Its illegal in my state so i can only get what my dealer has but i know at least 10 dealers that can get it.) i was doing it everyday for about 1 year and a half maybe 2 first tried it when i was still on the hydros so i've mixed hydromorphone and weed but thats not dangerous in my opinion you cant OD on green, ive done xanaxs off and on for 2-3 years (BTW i only do crack off and on when i feel like it and never more than 2-3 days at a time and also if you didn't know this the best thing to stop the withdrawal effect you feel like 10-15min after you run out 1mg of xanax is the best it stops it completely but ive never been addicted to crack its more of a when i feel like it/have the extra cash what i mean by the withdrawal is the jonesying effect of wanting more and more. ive done adderall but that was in like 4th to 6th grade because idiot doctor thought i had ADD and i dont but i didnt mind i liked it helped me pay attention and get better grades during that time so whatever haven't done it since never seen any around OTS. ive tried klonopin but didnt like it at much prefer xanax. Lets see thats it besides from salvia just to see if it was like weed like so many people said and its not dont do it, it sucks ass i hated the feeling. I stay away from hallucinogens i just dont think i'd like it, the only drugs i've mixed it klonopin and pain meds but the normal amount i never take anything extreme, xanax and pain meds normally only near bedtime and i do 1-2mg but normally 1mg xanax with 10-20mg oxymorphone but normally 10mg, only do 2mg and 20mg if im hurting bad (I have chronic pancreatitis). I've mixed weed with alot of drugs pretty much every drug i've listed that ive tried except meth, salvia, crack, and adderall. I havnt exactly mixed crack and xanax but after i run out of crack i do 1mg xanax about 10min after. Thats all i've ever mixed that could potentially be dangerous but i know my tolerance and have a very high pain med tolerance so im sure mixing some of what i have mixed for a newbie to pain med would lead to a OD but you have to know your tolerance. Be safe don't mix it unless you've had the drug by itself before and know what it does to you and also dont over do it, it wont hurt to try a small amount see how that does then do a little more until you reach the desired effect. Sorry for long post but i've done alot and mixed alot but i am as safe as i can be when mixing and don't mix anything that would lead to a OD to me personally but like i said before every drug effects everyone differently. Oh also i've done suboxone before but i wouldnt really call that a dangerous drug unless youve never done pain meds and take a sub but i dont know for sure, Ive mixed subs with xanax before with green before and with oxys before but it blocks most of the pain med if not all depends on how long youve been taking subs and how much a day. When i do have to take it i only take half a strip twice a day but normally dont have to do it longer than 1-2 days but soon i'm going clean and suboxone and marijuana will be the only drugs ill be on so wish me luck guys i'm going cross country in an RV with my brother for a long time so we can stop together. Wish us both luck and if your addicted it's your choice to stop or not i dont see anything wrong with any of these drugs except meth, and heroin. As long as you dont over do any of these drugs ive done then i see no problem with it but im at the point where they dont do anything for me but keep me from getting sick so me and my brother are done and getting clean our way. Hope you guys take this to heart and don't do anything stupid. and have a happy new year.
 
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Jimmyg10

Greenlighter
Joined
Dec 27, 2017
Messages
3
Took 1gram of good coke over the night, can I take 20mg zolpidem (stilnox) for the comedown to go to sleep, I usually use Valium, but don’t have any atm
 

Scrofula

Bluelight Crew
Joined
Apr 27, 2017
Messages
5,420
Location
California
It's no more dangerous than the Valium, and should work just as well. Some'll argue it won't help as much with anxiety.
 

RachelAlissa94

Greenlighter
Joined
Jan 15, 2018
Messages
1
Is Suboxone and Adderall dangerous together? I?m currently on 8mg a day of Suboxone, well zubsolv now, And was wondering if I can also take a 30mg of Adderall the same day
 
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